松田侑大

マツダユウダイ | Matsuda Yudai

所属機関・部署：
職名：副教授
ホームページURL (1件)： http://staffweb1.cityu.edu.hk/ymatsuda/

研究分野 (2件)：生物有機化学 , 環境、天然医薬資源学

研究キーワード (4件)：天然物化学 , 生合成 , 糸状菌 , ゲノムマイニング

競争的資金等の研究課題 (15件)：

2025 - 2027 Global genome mining in fungi for the discovery of hidden families of biosynthetic enzymes and associated natural products
2023 - 2026 Global genome mining for unexploited bioactive natural products in filamentous fungi
2022 - 2024 Broadening the chemical space of fungal meroterpenoids and the enzymatic repertoire for their biosynthesis
2020 - 2022 Comprehensive Understanding and Engineering of Fungal Xanthone Biosynthesis
2020 - 2022 Synthetic Biological Studies on Fungal Antitumor Polyketides Violaceoids by Utilizing the Replication-Cycle Reaction Method

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論文 (50件)：

Longhui Yu, Hiroshige Ogawa, Shangzhao Li, Tsoh Lam Cheung, Wenchao Liu, Dexiu Yan, Yudai Matsuda, Yusuke Kobayashi, Zhihong Guo, Kotaro Ikeda, et al. Concise Synthesis of Cyctetryptomycin A and B Enabled by Zr-Catalyzed Dimerization. Angewandte Chemie International Edition. 2024. e202414295
Hang Wang, Chao Peng, Xiao-Xuan Chen, Hao-Yang Wang, Run Yang, Hao Xiang, Qiu-Fen Hu, Ling Liu, Lung Wa Chung, Yudai Matsuda, et al. Structural and Computational Insights into the Noncanonical Aromatization in Fungal Polyketide Biosynthesis. ACS Catalysis. 2024. 10796-10805
Jia Tang, Yudai Matsuda. Discovery of fungal onoceroid triterpenoids through domainless enzyme-targeted global genome mining. Nature Communications. 2024. 15. 1
Qiaolin Ji, Hao Xiang, Wei Guang Wang, Yudai Matsuda. Mechanism Behind the Programmed Biosynthesis of Heterotrimeric Fungal Depside Thielavin A. Angewandte Chemie - International Edition. 2024. 63. 20
Dexiu Yan, Yudai Matsuda. Global genome mining-driven discovery of an unusual biosynthetic logic for fungal polyketide-terpenoid hybrids. Chemical Science. 2024. 15. 8. 3011-3017

MISC (9件)：

Jia Tang, Yudai Matsuda. Functional analysis of transmembrane terpene cyclases involved in fungal meroterpenoid biosynthesis. Methods in Enzymology. 2024
董佳钰, 李敏, 肖宗华, 胡明, Yudai Matsuda, 汪伟光. 米曲霉异源表达天然产物研究进展. 合成生物学. 2023. 3. 6. 1126-1149
Xingxing Wei, Wei Guang Wang, Yudai Matsuda. Branching and converging pathways in fungal natural product biosynthesis. Fungal Biology and Biotechnology. 2022. 9. 1
Yudai Matsuda, Ikuro Abe. Fungal Meroterpenoids. Comprehensive Natural Products III: Chemistry and Biology, Chapter 14. 2020. 445-478
Hitomi Nakamura, Yudai Matsuda, Ikuro Abe. Unique chemistry of non-heme iron enzymes in fungal biosynthetic pathways. Natural Product Reports. 2018. 35. 7. 633-645

講演・口頭発表等 (56件)：

Global Genome Mining in Fungi for Natural Product Discovery
(2024 US-Japan Seminar on the Biosynthesis of Natural Products)
Global genome mining in fungi for natural product discovery
(Frontiers in Medicinal Chemistry: A Forum for Innovation and Discovery)
Oxidative rearrangements in fungal meroterpenoid biosynthesis
(2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics (2023 ICCP450/JSSX))
糸状菌由来デプシド合成酵素の探索と機能解析
(第65回天然有機化合物討論会 2023)
Biosynthesis of Fungal Meroditerpenoids Setosusin and Brevione E
(2nd JNU-UTokyo Joint Seminar on Natural Product Biosynthesis)

学歴 (3件)：

学位 (1件)：

経歴 (8件)：

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受賞 (7件)：

2023/10 - Stanford University Stanford's top 2% most highly cited scientists 2023
2022/11 - Stanford University Stanford's top 2% most highly cited scientists 2022
2017/02 - 公益財団法人井上科学振興財団井上研究奨励賞
2016/09 - Reaxys Finalist, Reaxys PhD Prize
2015/06 - Novo Nordisk Foundation Postdoctoral fellowships for research within biotechnology-based synthesis and production

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松田 侑大