Watanabe-Takahashi M, Senda M, Yoshino R, Hibino M, Hama S, Terada T, Shimizu K, Senda T, Nishikawa K. A unique peptide-based pharmacophore identifies an inhibitory compound against the A-subunit of Shiga toxin. Scientific Reports. 2022. 12:11443
Miho Watanabe-Takahashi, Masakazu Tamada, Miki Senda, Masahiro Hibino, Eiko Shimizu, Akiko Okuta, Atsuo Miyazawa, Toshiya Senda, Kiyotaka Nishikawa. Identification of a peptide motif that potently inhibits two functionally distinct subunits of Shiga toxin. Communications Biology. 2021. 4. 1
Waka Sato, Miho Watanabe-Takahashi, Takashi Hamabata, Koichi Furukawa, Satoru Funamoto, Kiyotaka Nishikawa. A nontoxigenic form of Shiga toxin 2 suppresses the production of amyloid β by altering the intracellular transport of amyloid precursor protein through its receptor-binding B-subunit. Biochemical and Biophysical Research Communications. 2021. 557. 247-253
Jumpei Omi, Miho Watanabe-Takahashi, Katsura Igai, Eiko Shimizu, Ching-Yi Tseng, Tomohiro Miyasaka, Tsuyoshi Waku, Shinichiro Hama, Rieka Nakanishi, Yuki Goto, et al. The inducible amphisome isolates viral hemagglutinin and defends against influenza A virus infection. Nature communications. 2020. 11. 1. 162-162
デブリン生化学原書7版-臨床の理解のために(Textbook of Biochemistry with Clinical Correlations, 7th Edition)
丸善出版 2012
図説薬理学のポイント("Pretty done quick; Pharmacology, by Johnson, G. E., Brian C. Decker, Inc., 1988")
医学書院 1991
講演・口頭発表等 (9件):
COVID-19, Influenza related topics.
(DOSHISHA WEEK 2020/Webinar, COVOD-19 Research: Challenges and Achievements for the Society 2021)
Strategic development of peptide-based therapeutic agents against bacterial and viral infections
(The 16th Awaji International Forum on Infection and Immunity 2017)
Peptide-based Stx-neutralizers of treatment of STEC infections
(Seminar Series Fall 2015, Pathology and Laboratory Medicine 2015)
Peptide-based Stx-neutralizers of treatment of STEC infections
(International Symposium “New trends of anti-infection strategy” on The 86th Annual Meeting of Japanese Society For Microbiology 2013)
Peptide-based neutralizers of Shiga toxin
(International Union of Microbiological Societies 2011 Congress (IUMS2011) 2011)
1995 - 1998 Harvard Medical School/Beth Israel Deaconess Medical Center, Division of Signal Transduction, Visiting Assistant Professor
1989 - 1997 慶應義塾大学医学部薬理学教室 助手
受賞 (2件):
2013 - バイオビジネスアワードJAPAN彩都賞
2012 - The prize for the Best Poster on Prevention, Control and Treatment: Animal and Human at the 8th International Symposium on Shiga toxin (Verocytotoxin) Producing Escherichia coli Infections