神津 知子

• 機能性RNAを用いたがん診断治療法の開発

• Kenta Takada, Ryo Amano, Yusuke Nomura, Yoichiro Tanaka, Shigeru Sugiyama, Takashi Nagata, Masato Katahira, Yoshikazu Nakamura, Tomoko Kozu, Taiichi Sakamoto. Characterisation of an aptamer against the Runt domain of AML1 (RUNX1) by NMR and mutational analyses. FEBS Open Bio. 2018. 8. 2. 264-270
• Yusuke Nomura, Kaori Yamazaki, Ryo Amano, Kenta Takada, Takashi Nagata, Naohiro Kobayashi, Yoichiro Tanaka, Junichi Fukunaga, Masato Katahira, Tomoko Kozu, et al. Conjugation of two RNA aptamers improves binding affinity to AML1 Runt domain. JOURNAL OF BIOCHEMISTRY. 2017. 162. 6. 431-436
• Ryo Amano, Kazuteru Aoki, Shin Miyakawa, Yoshikazu Nakamura, Tomoko Kozu, Gota Kawai, Taiichi Sakamoto. NMR monitoring of the SELEX process to confirm enrichment of structured RNA. SCIENTIFIC REPORTS. 2017. 7. 1. 283
• Ryo Amano, Kenta Takada, Yoichiro Tanaka, Yoshikazu Nakamura, Gota Kawai, Tomoko Kozu, Taiichi Sakamoto. Kinetic and Thermodynamic Analyses of Interaction between a High Affinity RNA Aptamer and Its Target Protein. BIOCHEMISTRY. 2016. 55. 45. 6221-6229
• Yusuke Nomura, Yoichiro Tanaka, Jun-ichi Fukunaga, Kazuya Fujiwara, Manabu Chiba, Hiroaki Iibuchi, Taku Tanaka, Yoshikazu Nakamura, Gota Kawai, Tomoko Kozu, et al. Solution structure of a DNA mimicking motif of an RNA aptamer against transcription factor AML1 Runt domain. JOURNAL OF BIOCHEMISTRY. 2013. 154. 6. 513-519

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• - 1974 国際基督教大学 教養学部 自然科学科
• - 1974 国際基督教大学

• 博士(薬学) (東京大学)

日本分子生物学会 ,  日本生化学会 ,  日本癌学会 ,  日本RNA学会 ,  アジア環太平洋地域国際分子生物学ネットワーク ,  RNA学会(米国) ,  The RNA Society of Japan ,  The Molecular Biology Society of Japan ,  The Japanese Society of Hematology ,  The Japanese Cancer Association ,  The Japanese Biochemical Society ,  Asia-Pacific International Molecular Biology Network ,  The RNA Society(USA)