白藤 尚毅

• 造血幹細胞に働く成長因子の同定の研究
• 白血病に対する遺伝子治療の基礎的研究
• Isolation and characterization of growth fuctor which can work on hematopoictic stem cells.
• Fundamental Study of gene therapy for leukemias

• Tashiro H, Shirasaki R, Watanabe M, Kawasugi K, Takahashi Y, Shirafuji N. Direct Factor X sequestration by systemic amyloid light-chain amyloidosis. Clinical case reports. 2018. 6. 3. 513-515
• Yoko Oka, Haruko Tashiro, Ryosuke Sirasaki, Tadashi Yamamoto, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji, Shin Fujimori. HYPERURICEMIA IN HEMATOLOGIC MALIGNANCIES IS CAUSED BY AN INSUFFICIENT URINARY EXCRETION. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS. 2014. 33. 4-6. 434-438
• Mayumi Yoshimi, Susumu Goyama, Masahito Kawazu, Masahiro Nakagawa, Motoshi Ichikawa, Yoichi Imai, Keiki Kumano, Takashi Asai, James C. Mulloy, Andrew S. Kraft, et al. Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation. EUROPEAN JOURNAL OF IMMUNOLOGY. 2012. 42. 4. 1044-1050
• Ryosuke Shirasaki, Haruko Tashiro, Yoko Oka, Takuji Matsuo, Tadashi Yamamoto, Toshihiko Sugao, Nobu Akiyama, Kazuo Kawasugi, Naoki Shirafuji. Chronic myelogenous leukemia cells contribute to the stromal myofibroblasts in Leukemic NOD/SCID mouse in vivo. Journal of Oncology. 2012. 2012. 901783
• Sugimoto-Sekiguchi H, Tashiro H, Shirasaki R, Arai T, Yamamoto T, Oka Y, Akiyama N, Kawasugi K, Shirafuji N. Colonic EBV-Associated Lymphoproliferative Disorder in a Patient Treated with Rabbit Antithymocyte Globulin for Aplastic Anemia. Case reports in gastrointestinal medicine. 2012. 2012. 395801-395801

もっと見る

• N Shirafuji, S Takahashi, S Matsuda, S Asano. Mitochondrial antisense RNA for cytochrome C oxidase (MARCO) can induce morphologic changes and cell death in human hematopoietic cell lines. BLOOD. 1997. 90. 11. 4567-4577
• T TANAKA, S AKIRA, K YOSHIDA, M UMEMOTO, Y YONEDA, N SHIRAFUJI, H FUJIWARA, S SUEMATSU, N YOSHIDA, T KISHIMOTO. TARGETED DISRUPTION OF THE NF-IL6 GENE DISCLOSES ITS ESSENTIAL ROLE IN BACTERIA KILLING AND TUMOR-CYTOTOXICITY BY MACROPHAGES. CELL. 1995. 80. 2. 353-361
• Recombinant human glycosylated granulocyte colony-stimulating factor CrhG-(SF)-combined reginen for allugeneic bonemarrow tyansplantation in refractony acute myeloid leukemia. Bone Marrow Transplantation. 1994. 13. 239
• Expression of granuloalte and granuloute-macrophage colony-stimulating factors by human nru-hematopoietic tumor colls. Growth Factors. 1990. 3. 325
• Granulocyte colony-stimulating factor stimulates human mature neutrophilic granulocytes to produce interferon-α. BLOOD. 1990. 75. 1. 17

もっと見る

• siRNAを用いた血液腫瘍の治療実研
  2003 -
• 白血病に関する多型性の研究
  2002 -

• - 1982 東京大学 医学部 医
• - 1982 東京大学

• 博士(医学) (東京大学)

日本検査血液学会 ,  International Sciety of Experimental Hematology ,  European Society of Gene Therapy ,  American Society of Hematology ,  日本内科学会 ,  日本造血細胞移植学会 ,  American society of Gene Therapy ,  日本遺伝子治療学会 ,  日本臨床血液学会 ,  日本血液学会 ,  American Society of Gene Therapy ,  International Society for Cellular Therapy