松本明郎

マツモトアキオ | Matsumoto Akio

所属機関・部署：
職名：教授

研究分野 (7件)：呼吸器内科学 , 循環器内科学 , 病態医化学 , 医化学 , 薬理学 , 細胞生物学 , 分子生物学

研究キーワード (6件)：ガス薬理学 , Glycosylation , Signal transduction , Posttranslational modifications , S-nitrosylation , Nitric Oxide

競争的資金等の研究課題 (2件)：

一酸化窒素によるシグナル伝達制御系の解明
-

論文 (85件)：

Hiroko Izumi-Nakaseko, Koki Chiba, Ai Goto, Ryuichi Kambayashi, Akio Matsumoto, Yoshinori Takei, Shinichi Kawai, Atsushi Sugiyama. Electropharmacological Characterization of Licorice Using the Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Sheets and the Chronic Atrioventricular Block Dogs. Cardiovascular toxicology. 2023. 23. 5-6. 207-217
Hiroko Izumi-Nakaseko, Kengo Sakamoto, Ai Goto, Ryuichi Kambayashi, Akio Matsumoto, Yoshinori Takei, Akira Takahara, Atsushi Sugiyama. Characterization of pathological remodeling in the chronic atrioventricular block cynomolgus monkey heart. Frontiers in pharmacology. 2023. 14. 1055031-1055031
Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Ai Goto, Yoshinori Takei, Akio Matsumoto, Ulrike Lorch, Jörg Täubel, Atsushi Sugiyama. Both osmolality-dependent and independent mechanisms are associated with acute hyperglycemia-induced cardiovascular adverse reactions: Analysis of the mutual interactions leading to cardiovascular phenotypes in dogs. The Journal of toxicological sciences. 2023. 48. 3. 169-178
Ryuichi Kambayashi, Ai Goto, Hiroko Izumi-Nakaseko, Ichiro Oikawa, Naoki Ikeda, Kazuki Matsuda, Yoshinori Takei, Akio Matsumoto, Yuji Kumagai, Atsushi Sugiyama. Appraisal of ICH E14/S7B Q&As adopted in February 2022 using thorough QT/QTc study data for α4-integrin antagonist carotegrast methyl in Japanese healthy subjects. Journal of pharmacological sciences. 2022. 150. 3. 191-199
Ai Goto, Kengo Sakamoto, Ryuichi Kambayashi, Hiroko Izumi-Nakaseko, Shinichi Kawai, Yoshinori Takei, Akio Matsumoto, Yasunari Kanda, Atsushi Sugiyama. Validation of Risk-Stratification Method for the Chronic Atrioventricular Block Cynomolgus Monkey Model and Its Mechanistic Interpretation Using 6 Drugs With Pharmacologically Distinct Profile. Toxicological sciences : an official journal of the Society of Toxicology. 2022. 190. 1. 99-109

MISC (137件)：

Goto A†, Kambayashi R†, Hagiwara-Nagasawa M†, Izumi-Nakaseko H†, Takei Y†, Kawai S†, Matsumoto A†, Lurie K, Sugiyama A*†. Impact of head-up tilt on expiratory negative airway pressure ventilation-induced cardiovascular hemodynamics in the halothane-anesthetized intact microminipigs. Heart and vessels. 2022. 37. 10. in press-1815
Kambayashi R†, Goto A†, Izumi-Nakaseko H†, Matsumoto A†, Sugiyama A*†. Measurement of early and late repolarization periods in addition to QT interval to help predict the torsadogenic risk of donepezil based on reverse translational animal research on its proarrhythmic potential. Circulation Reports. 2021. 3. 9. 555-556
Hagiwara-Nagasawa M†, Kambayashi R†, Goto A†, Chiba K†, Wada T†, Nunoi Y†, Izumi-Nakaseko H†, Takei Y†, Matsumoto A†, Lurie KG, et al. Effects of mechanical ventilation with expiratory negative airway pressure on porcine pulmonary and systemic circulation: mechano-physiology and potential application. The Journal of Physiological Sciences. 2021. 71. 1. in press-17
Goto A†, Sakamoto K, Hagiwara-Nagasawa M†, Kambayashi R†, Chiba K†, Nunoi Y†, Izumi-Nakaseko H†, Takei Y†, Matsumoto A†, Sugiyama A*†. In vivo analysis of the effects of intravenously as well as orally administered moxifloxacin on the pharmacokinetic and electrocardiographic variables along with its torsadogenic action in the chronic atrioventricular block cynomolgus monkeys. Journal of Pharmacological Sciences. 2020. 143. 4. 272-280
清水健, 村田正太, 石毛昭太, 甲斐心皓, 三塚康ノ介, 富田治芳, 谷本弘一, 松本明郎. 緑膿菌の一酸化窒素抵抗性に対するマクロライドの効果. 日本細菌学雑誌. 2020. 75. 1. 144-144

特許 (4件)：

Works (2件)：

血管内皮細胞における糖鎖メカノセンサーの探索
2008 -
糖鎖シグナルの異常による肺気腫の発生機構の解明と治療戦略
2006 -

学位 (1件)：

博士(医学) (北海道大学)

経歴 (3件)：

2018/12 - 現在東邦大学医学部・加齢薬理学教授(寄付講座)
2009/04 - 2018/12 千葉大学大学院医学研究院薬理学准教授
2006/07 - 2009/03 大阪大学微生物病研究所疾患糖鎖学寄付研究部門准教授

受賞 (2件)：

2004 - Young Investigator Award (1st place)
2004 - Young Investigator Award (1st place)

所属学会 (5件)：

日本NO学会 , 日本心臓病学会 , 日本循環器学会 , 日本内科学会 , 日本薬理学会

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松本 明郎

松本明郎