2002 - 2004 Reduction of Extra-mitochondrial Coenzyme Q and its Physiological Roles
1997 - 1998 酸化ストレス負荷時の筋細胞応答能と生体内抗酸化剤の変動
1996 - 1998 生体抗酸化系におけるユビキノンの生理的役割に関する研究
論文 (5件):
Yukitoshi Mine, Takayuki Takahashi, Tadashi Okamoto. Stimulatory effects of collagen production induced by coenzyme Q10 in cultured skin fibroblasts. Journal of Clinical Biochemistry and Nutrition. 2022. 71. 1. 29-33
Yukitoshi Mine, Takayuki Takahashi, Tadashi Okamoto. Protective effects of coenzyme Q10 on cell damage induced by hydrogen peroxides in cultured skin fibroblasts. Journal of Clinical Biochemistry and Nutrition. 2021. 69. 3. 247-255
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. Extracellular coenzyme Q10 (CoQ10) is reduced to ubiquinol-10 by intact Hep G2 cells independent of intracellular CoQ10 reduction. Archives of Biochemistry and Biophysics. 2019. 672. 108067-108067
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. 2,3-Dimethoxy-5-methyl-p-benzoquinone (Coenzyme Q0) Disrupts Carbohydrate Metabolism of HeLa Cells by Adduct Formation with Intracellular Free Sulfhydryl-Groups, and Induces ATP Depletion and Necrosis. Biological and Pharmaceutical Bulletin. 2018. 41. 12. 1809-1817
Takayuki Takahashi, Yukitoshi Mine, Tadashi Okamoto. Intracellular reduction of coenzyme Q homologues with a short isoprenoid side chain induces apoptosis of HeLa cells. The Journal of Biochemistry. 2018. 163. 4. 329-339