西村健

ニシムラケン | NISHIMURA Ken

所属機関・部署：
職名：教授

研究分野 (1件)：医化学

研究キーワード (1件)：幹細胞工学、遺伝子発現制御

競争的資金等の研究課題 (19件)：

全件表示

論文 (69件)：

Jingwen Zhou, Yuya Sekiguchi, Masayuki Sano, Ken Nishimura, Koji Hisatake, Aya Fukuda. A Sendai virus-based expression system directs efficient induction of chondrocytes by transcription factor-mediated reprogramming. Scientific reports. 2024. 14. 1. 26004-26004
Utsugi, Yuki, Nishimura, Ken, Yamanaka, Satoshi, Nishino, Kohei, Kosako, Hidetaka, Sawasaki, Tatsuya, Shigemori, Hideyuki, Wandless, Thomas J, Miyamae, Yusaku. Ubiquitin-Derived Fragment as a Peptide Linker for the Efficient Cleavage of a Target Protein from a Degron. ACS CHEMICAL BIOLOGY. 2024. 19. 2. 497-505
Takumi Kishimoto, Ken Nishimura, Kana Morishita, Aya Fukuda, Yusaku Miyamae, Yutaro Kumagai, Kimio Sumaru, Mahito Nakanishi, Koji Hisatake, Masayuki Sano. An engineered ligand-responsive Csy4 endoribonuclease controls transgene expression from Sendai virus vectors. Journal of biological engineering. 2024. 18. 1. 9-9
Takeda, Nobutaka, Tsuchiya, Atsunori, Mito, Masaki, Natsui, Kazuki, Natusi, Yui, Koseki, Yohei, Tomiyoshi, Kei, Yamazaki, Fusako, Yoshida, Yuki, Abe, Hiroyuki, et al. Analysis of distribution, collection, and confirmation of capacity dependency of small extracellular vesicles toward a therapy for liver cirrhosis. INFLAMMATION AND REGENERATION. 2023. 43. 1
Sekiguchi, Yuya, Fukuda, Aya, Nishimura, Ken, Hisatake, Koji. Engineering Critical Residues of SOX9 Discovers a Variant With Potent Capacity to Induce Chondrocytes. STEM CELLS. 2023. Epub

MISC (3件)：

Ken Nishimura, Hiroaki Segawa, Mahito Nakanishi. Development of novel defective sendai virus vectors capable of expressing therapeutic genes persistently. JOURNAL OF GENE MEDICINE. 2008. 10. 4. 444-444
Ken Nishimura, Hiroaki Segawa, Takahiro Goto, Mariko Morishita, Takemasa Sakaguchi, Tetsuya Yoshida, Kozo Takayama, Mahito Nakanishi. Persistent gene expression from a novel RNA virus vector based on Sendai virus cl.151 STRAIN. JOURNAL OF GENE MEDICINE. 2006. 8. 12. 1457-1457
Takahiro Goto, Mariko Morishita, Ken Nishimura, Mahito Nakanishi, Atsushi Kato, Jumpei Ehara, Kozo Takayama. Novel mucosal insulin delivery systems based on fusogenic liposomes. Pharmaceutical research. 2006. 23. 2. 384-91

特許 (7件)：

講演・口頭発表等 (63件)：

軟骨分化を促進する新規SOX9変異体の同定
(第36回日本軟骨代謝学会)
切除可能なデグロンを用いた細胞内標的タンパク質発現制御手法の開発
(日本農芸化学会関東支部2023年度大会)
切除可能なデグロンを用いた細胞内標的タンパク質発現制御手法の開発
(日本ケミカルバイオロジー学会第17回年会)
Mechanistic analysis of chromosome-wide epigenetic change during iPSC generation using Klf4-dose dependent reprogramming system
(The 20th International Joint Mini-Symposium on Molecular and Cell Biology among KU-NTU-UT)
iPS細胞誘導過程において二相性の機能を有するE2F4の解析
(第45回日本分子生物学会年会)

経歴 (1件)：

受賞 (1件)：

所属学会 (2件)：

日本再生医療学会 , 日本分子生物学会

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西村 健