青木俊二

Aoki Shunji

研究分野 (1件)：生物分子化学

研究キーワード (2件)：天然薬物学 , Biological Organic Chemistry

競争的資金等の研究課題 (2件)：

論文 (24件)：

Dexin Kong, Shunji Aoki, Yoshihiro Sowa, Toshiyuki Sakai, Motomasa Kobayashi. Smenospongine, a sesquiterpene aminoquinone from a marine sponge, induces G1 arrest or apoptosis in different leukemia cells. Marine Drugs. 2008. 6. 3. 480-488
Naoyuki Kotoku, Atsushi Hiramatsu, Hiroaki Tsujita, Yoichi Hirakawa, Mami Sanagawa, Shunji Aoki, Motomasa Kobayashi. Structure-activity relationships study of bastadin 6, an anti-angiogenic brominated-tyrosine derived metabolite from marine sponge. ARCHIV DER PHARMAZIE. 2008. 341. 9. 568-577
Shunji Aoki, Yasuo Watanabe, Daiki Tanabe, Masayoshi Arai, Hideaki Suna, Katsushiro Miyamoto, Hiroshi Tsujibo, Kazutake Tsujikawa, Hiroshi Yamamoto, Motomasa Kobayashi. Structure-activity relationship and biological property of cortistatins, anti-angiogenic spongean steroidal alkaloids. Bioorganic and Medicinal Chemistry. 2007. 15. 21. 6758-6762
Taka-Aki Matsui, Yoshihiro Sowa, Hiroaki Murata, Koichi Takagi, Ryoko Nakanishi, Shunji Aoki, Masayuki Yoshikawa, Motomasa Kobayashi, Tomoya Sakabe, Toshikazu Kubo, et al. The plant alkaloid cryptolepine induces p21WAF1/CIP1 and cell cycle arrest in a human osteosarcoma cell line. International Journal of Oncology. 2007. 31. 4. 915-922
Hideaki Suna, Shunji Aoki, Andi Setiawan, Motomasa Kobayashi. Crambescidin 800, a pentacyclic guanidine alkaloid, protects a mouse hippocampal cell line against glutamate-induced oxidative stress. Journal of Natural Medicines. 2007. 61. 3. 288-295

MISC (39件)：

Yasuo Watanabe, Shunji Aoki, Daiki Tanabe, Andi Setiawan, Motomasa Kobayashi. Cortistatins E, F, G, and H, four novel steroidal alkaloids from marine sponge Corticium simplex. TETRAHEDRON. 2007. 63. 19. 4074-4079
Shunji Aoki, Seok Hwan Cho, Mayumi Ono, Takashi Kuwano, Shintaro Nakao, Michihiko Kuwano, Shinsaku Nakagawa, Jian Qing Gao, Tadanori Mayumi, Masabumi Shibuya, et al. Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells. Anti-Cancer Drugs. 2006. 17. 269-278
Tomohiro Noguchi, Xiao-Qin Ren, Shunji Aoki, Yoshinobu Igarashi, Xiao-Fang Che, Yuichi Nakajima, Homare Takahashi, Ryoichi Mitsuo, Kazutake Tsujikawa, Tomoyuki Sumizawa, et al. MRP1 mutated in the L0 region transports SN-38 but not Leukotriene C4 or estradiol-17 (-D-glucuronate). Biochem. Pharmacol. 2005. 70. 7. 1056-1065
H Wei, T Itoh, M Kinoshita, N Kotoku, S Aoki, M Kobayashi. Shimalactone A, a novel polyketide, from marine-derived fungus Emericella variecolor GF10. TETRAHEDRON. 2005. 61. 33. 8054-8058
N Kotoku, LW Cao, S Aoki, M Kobayashi. Absolute stereo-structure of kendarimide a, a novel MDR modulator, from a marine sponge. HETEROCYCLES. 2005. 65. 3. 563-578

Works (2件)：

学位 (2件)：

所属学会 (4件)：

ÇTMÇÒïTMéqïWìIé°ó√å§ãÜâÔÅ , 日本生薬学会 , 日本癌学会 , 日本薬学会

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青木 俊二