臼杵扶佐子

Usuki Fusako

研究分野 (2件)：神経内科学 , 病態医化学

研究キーワード (10件)： ER stress プレコンデイショニング , シグナル伝達系、 , Nonsense-mediated mRNA decay , アポトーシス , 酸化ストレス , メチル水銀 , 環境ストレス , methylmercury nonsense-mediated mRNA decay , apoptosis , oxidative stress

論文 (56件)：

Masatake Fujimura, Fusako Usuki. Methylmercury induces oxidative stress and subsequent neural hyperactivity leading to cell death through the p38 MAPK-CREB pathway in differentiated SH-SY5Y cells. NeuroToxicology. 2018. 67. 226-233
Masatake Fujimura, Fusako Usuki. In situ different antioxidative systems contribute to the site-specific methylmercury neurotoxicity in mice. TOXICOLOGY. 2017. 392. 55-63
Fusako Usuki, Masatake Fujimura, Akio Yamashita. Endoplasmic reticulum stress preconditioning modifies intracellular mercury content by upregulating membrane transporters. SCIENTIFIC REPORTS. 2017. 7. 1. 12390
Masatake Fujimura, Fusako Usuki. Site-specific neural hyperactivity via the activation of MAPK and PKA/CREB pathways triggers neuronal degeneration in methylmercury-intoxicated mice. TOXICOLOGY LETTERS. 2017. 271. 66-73
Tetsuya Takahashi, Masatake Fujimura, Misaki Koyama, Masato Kanazawa, Fusako Usuki, Masatoyo Nishizawa, Takayoshi Shimohata. Methylmercury Causes Blood-Brain Barrier Damage in Rats via Upregulation of Vascular Endothelial Growth Factor Expression. PLOS ONE. 2017. 12. 1. e0170623

MISC (79件)：

Usuki F, Yamashita A, Higuchi I, Ohnishi T, Shiraishi T, Osame M, Ohno S: Inhibition of nonsense-mediated mRNA decay rescues the mutant phenotype in collagen VI-deficient Ullrich's disease. Ann Neurol. 2004. 55: 740-744
Usuki F, Yasutake A, Umehara F, Higuchi I: Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin. Acta Neuropathologica. 2004. 108, 1-9
Usuki F, Yamashita A, Higuchi I, Ohnishi T, Shiraishi T, Osame M, Ohno S: Inhibition of nonsense-mediated mRNA decay rescues the mutant phenotype in collagen VI-deficient Ullrich's disease. Ann Neurol. 2004. 55, 740-744
Usuki F, Yasutake A, Umehara F, Higuchi I: Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin. Acta Neuropathologica. 2004. 108, 1-9
臼杵扶佐子: 酸性マルターゼ欠損のないリソゾームグリコーゲン蓄積症(Danon 病)日本臨床. 先天代謝異常症候群 (下) 353-355, 1998

委員歴 (2件)：

2001 - 日本神経学会評議員
2001 - The Japanese Society of Neurology Councilor

所属学会 (8件)：

日本分子生物学会 , 日本内科学会 , 日本生化学学会 , 日本神経学会 , The Molecular Biology Society of Japan , The Japanese Society of Neurology , The Japanese Society of Internal Medicine , The Japanese Biochemical Society

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