研究キーワード (6件):
Drug absorption and excreation
, 薬物の腎排泄および消化管吸収
, Preparation and Evaluation of Solid Dispersions.
, 固体分散体製剤の調製と評価
, Drug release from oral mucosal adhesive tablets and films.
, 口腔粘膜付着性製剤
競争的資金等の研究課題 (5件):
2003 - 2004 P-糖たん白基質薬物の体内動態に及ぼす性周期の影響
1998 - 1999 消化管吸収抑制機構の気質認識特性とその発見メカニズムの解明
1994 - 1995 薬物治療への超音波の有効利用:パルス照射による経皮治療システムの研究
薬物の吸収・排泄における機構の解明
Study of the mechanisms of drug absorption and renal excretion
論文 (19件):
Yuichi Ichimura, Natsumi Kudoh, Takashi Murabe, Takumi Akao, Sho Watanuki, Takanao Suzuki, Toshihide Saito, Masako Oda, Hiroshi Saitoh. Inhibitory effects of indoxyl sulfate and creatinine on the renal transport of meropenem and biapenem in rats. Drug Metabolism and Pharmacokinetics. 2021. 40. 100406-100406
Fuyo Takeda, Masako Oda, Masaru Terasaki, Yuichi Ichimura, Hiroyuki Kojima, Hiroshi Saitoh. Downregulated expression of intestinal P-glycoprotein in rats with cisplatin-induced acute kidney injury causes amplification of its transport capacity to maintain “gatekeeper” function. Toxicology and Applied Pharmacology. 2021. 423. 115570-115570
Fuyo Takeda, Masako Oda, Masaru Terasaki, Atsuhito Kubota, Keita Asada, Yuichi Ichimura, Hiroyuki Kojima, Hiroshi Saitoh. Downregulated expression of organic anion transporting polypeptide (Oatp) 2b1 in the small intestine of rats with acute kidney injury. Drug metabolism and pharmacokinetics. 2021. 40. 100411-100411
Hideyuki Suga, Yuichi Ichimura, Masako Oda, Hiroshi Saitoh. Different Correlation between Serum Levels of Indoxyl Sulfate and Estimated GFR in the Elderly with or without Dementia. BPB Reports. 2020. 3. 3. 102-105
Hideyuki Suga, Yuichi Ichimura, Satomi Otsuka, Kaori Sugaya, Masako Oda, Hiroshi Saitoh. Limited Effect of Intravenously Administered Indoxyl Sulfate, a Uremic Toxin, on the Hepatic Transport of Pravastatin in Normal Rats. Pharmacology & Pharmacy. 2018. 09. 07. 270-278