文献

J-GLOBAL ID：200902236746367118   整理番号：09A0070900

S-1での隔日vs連日治療の比較 in vitroおよびin vivoでの胃癌細胞株の腫瘍増殖阻害および毒性減少の評価

Comparison of alternate-day versus consecutive-day treatment with S-1: assessment of tumor growth inhibition and toxicity reduction in gastric cancer cell lines in vitro and in vivo

著者 (13件)： ARAI Wataru (Jichi Medical Univ., Tochigi, JPN) ,  HOSOYA Yoshinori (Jichi Medical Univ., Tochigi, JPN) ,  HARUTA Hidenori (Jichi Medical Univ., Tochigi, JPN) ,  KURASHINA Kentaro (Jichi Medical Univ., Tochigi, JPN) ,  SAITO Shin (Jichi Medical Univ., Tochigi, JPN) ,  HIRASHIMA Yuuki (Jichi Medical Univ., Tochigi, JPN) ,  YOKOYAMA Taku (Jichi Medical Univ., Tochigi, JPN) ,  ZUIKI Toru (Jichi Medical Univ., Tochigi, JPN) ,  SAKUMA Kazuya (Jichi Medical Univ., Tochigi, JPN) ,  HYODO Masanobu (Jichi Medical Univ., Tochigi, JPN) ,  YASUDA Yoshikazu (Jichi Medical Univ., Tochigi, JPN) ,  NAGAI Hideo (Jichi Medical Univ., Tochigi, JPN) ,  SHIRASAKA Tetsuhiko (Kitasato Univ., Tokyo, JPN)
資料名： International Journal of Clinical Oncology  (International Journal of Clinical Oncology)
巻： 13  号： 6  ページ： 515-520  発行年： 2008年12月 
JST資料番号： L3966A  ISSN： 1341-9625  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： ドイツ (DEU)  言語： 英語 (EN)

抄録/ポイント： S-1の副作用により治療中断が発生する場合があり,副作用低減...

シソーラス用語： *胃腫瘍 ,...
準シソーラス用語： 隔日投与

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分類 (1件)： 抗腫よう薬の基礎研究  (GW16010A)

物質索引 (1件)： S-1

引用文献 (26件)：

• SHIRASAKA, T. Development of a novel form of 5-fluorouracil derivative (S-1) directed to the potentiation of the tumor selective cytotoxicity of 5-fluorouracil by two biochemical modulators. Anticancer Drugs. 1996, 7, 548-557
• SHIRASKA, T. Conceptual changes in cancer chemotherapy : from an oral fluoropyrimidene prodrug, UFT, to a novel oral fluoropyrimidine prodrug, S-1, and low-dose FP therapy in Japan. Invest New Drugs. 2000, 18, 315-329
• TATSUMI, K. Inhibitory effects of pyrimidine, barbituric acid and pyrimidine derivatives on 5-fluorouracil degradation in rat liver extracts. Jpn J Cancer Res. 1987, 78, 748-755
• SHIRASAKA, T. Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats. Cancer Res. 1993, 53, 4004-4009
• SAKATA, Y. Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1 M tegafur-0.4 M gimestat-1 M otastat potassium) in advanced gastric cancer patients. Eur J Cancer. 1998, 34, 1715-1720

タイトルに関連する用語 (9件)： S-1 ,  Vs ,  治療 ,  胃 ,  癌細胞株 ,  腫瘍増殖 ,  阻害 ,  毒性 ,  評価