2021 - 2024 Bile cell-free DNAを用いゲノム多様性を標的にした胆道癌新規治療
2018 - 2021 血液メタボロミクスによる胆嚢癌予後予測因子解析
2013 - 2016 胆道癌微小転移に対する間葉系幹細胞を用いた癌標的治療の開発
2010 - 2012 ユビキチンリガーゼFbw7によるタンパク質分解制御からの胆道癌発現機序解明
2010 - 2011 肝細胞冬眠誘導を用いた転移性肝癌に対する治療法の開発
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論文 (387件):
Shin Ito, Mika Ando, Shuichi Aoki, Satoshi Soma, Jie Zhang, Naohiro Hirano, Ryosuke Kashiwagi, Keigo Murakami, Shingo Yoshimachi, Hideaki Sato, et al. Usefulness of multigene liquid biopsy of bile for identifying driver genes of biliary duct cancers. Cancer science. 2024
Kent Miyazaki, Kyohei Ariake, Satoko Sato, Takayuki Miura, Jingyu Xun, Daisuke Douchi, Masaharu Ishida, Hideo Ohtsuka, Masamichi Mizuma, Kei Nakagawa, et al. GFPT2 expression is induced by gemcitabine administration and enhances invasion by activating the hexosamine biosynthetic pathway in pancreatic cancer. Clinical & Experimental Metastasis. 2024
Masahiro Iseki, Masamichi Mizuma, Mitsuhiro Shimura, Takashi Kokumai, Hideaki Sato, Akiko Kusaka, Shuichi Aoki, Koetsu Inoue, Shun Nakayama, Daisuke Douchi, et al. Preoperative chemotherapy with Gemcitabine for pancreatic cancer causes zinc deficiency. Pancreas. 2024
Yuko Omori, Shuichi Aoki, Yusuke Ono, Takashi Kokumai, Shingo Yoshimachi, Hideaki Sato, Akiko Kusaka, Masahiro Iseki, Daisuke Douchi, Takayuki Miura, et al. Clonal analysis of metachronous double biliary tract cancers. The Journal of pathology. 2024. 263. 1. 113-127
Naohiro Hirano, Masahiro Iseki, Kei Nakagawa, Masamichi Mizuma, Takashi Kamei, Ryotaro Matsumoto, Shin Miura, Kiyoshi Kume, Atsushi Masamune, Michiaki Unno. A case report of perihilar cholangiocarcinoma in a patient with situs inversus totalis. Clinical journal of gastroenterology. 2024