文献

J-GLOBAL ID：201002250987217943   整理番号：10A1043354

ラット大動脈平滑筋細胞においてガンボギン酸はPDGF受容体βチロシンリン酸化とRac1活性化の抑制を介したG0/G1細胞周期停止と細胞遊走阻止を誘導する

Gambogic Acid Induces G0/G1 Cell Cycle Arrest and Cell Migration Inhibition Via Suppressing PDGF Receptor β Tyrosine Phosphorylation and Rac1 Activity in Rat Aortic Smooth Muscle Cells

著者 (10件)： LIU Yong (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  LI Wen (Lab. of Dep. of Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  YE Caisheng (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  LIN Ying (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  CHEANG Tuck-yun (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  WANG Mian (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  ZHANG Hui (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  WANG Sanming (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  ZHANG Longjuan (Lab. of Dep. of Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.) ,  WANG Shenming (Dep. of Vascular Surgery, The First Affiliated Hospital, Sun Yat-sen Univ.)
資料名： Journal of Atherosclerosis and Thrombosis (Web)  (Journal of Atherosclerosis and Thrombosis (Web))
巻： 17  号： 9  ページ： 901-913 (J-STAGE)  発行年： 2010年 
JST資料番号： U0153A  ISSN： 1880-3873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:ガンボギン酸(GA)は東南アジアGarcinia ha...

シソーラス用語： *血管平滑筋細胞 ,...
準シソーラス用語： PDGFβ受容体 ,...

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分類 (1件)： 生薬の薬理の基礎研究  (GX06020J)

物質索引 (1件)： ガンボギン酸

引用文献 (40件)：

• 1) Xie QJ, Hou C, Wu WK: Study on platelet-derived growth factor mRNA and copper-zinc superoxide dis-mutase mRNA expression changes of aortic artery endo-thelium with restenosis after aortic artery dilatation treated with buyang huanwu decoction. Zhongguo Zhong Xi Yi Jie He Za Zhi, 1997; 17: 611-613
• 2) Yamasaki Y, Miyoshi K, Oda N, Watanabe M, Miyake H, Chan J, et al: Weekly dosing with the platelet-derived growth factor receptor tyrosine kinase inhibitor SU9518 significantly inhibits arterial stenosis. Circ Res, 2001; 88: 630-636
• 3) Sachinidis A, Locher R, Vetter W, Tatje D, Hoppe J: Dif-ferent effects of platelet-derived growth factor isoforms on rat vascular smooth muscle cells. J Biol Chem, 1990; 265: 10238-10243
• 4) Fishbein I, Waltenberger J, Banai S, Rabinovich L, Chorny M, Levitzki A, et al: Local delivery of platelet-derived growth factor receptor-specific tyrphostin inhibits neointimal formation in rats. Arterioscler Thromb Vasc Biol, 2000; 20: 667-676
• 5) Leppanen O, Janjic N, Carlsson MA, Pietras K, Levin M, Vargeese C, et al: Intimal hyperplasia recurs after removal of PDGF-AB and -BB inhibition in the rat carotid artery injury model. Arterioscler Thromb Vasc Biol, 2000; 20: E89-95

タイトルに関連する用語 (10件)： ラット ,  大動脈平滑筋細胞 ,  ガンボギン酸 ,  PDGF受容体β ,  チロシンリン酸化 ,  Rac1 ,  活性化 ,  細胞周期停止 ,  細胞遊走阻止 ,  誘導