JM Dijkstra

所属機関・部署：
職名：准教授
ホームページURL (1件)： http://kaken.nii.ac.jp/ja/r/10387681

研究分野 (3件)：免疫学 , 進化生物学 , 水圏生産科学

研究キーワード (20件)： Cytokines , MHC , Fish , Evolution , Immunology , 抗原提示 , 免疫システム , 原始的 , 獲得免疫 , MHC , 脊椎動物 , 分子ファミリー , 自然免疫 , 進化 , 分子進化 , 水産学 , 生体分子 , 免疫学 , 遺伝子 , ゲノム

競争的資金等の研究課題 (12件)：

2023 - 2026 Allergenicities of the multiple individual parvalbumins in fish
2022 - 2024 Harnessing interleukin 2 (LI-2) family power in fish; Study of rainbow trout IL-2, IL-15, IL-15L, and IL- 15Rα
2021 - Assessing protective immunity to COVID19 provided by prior seasonal coronavirus infection
2016 - 2019 Harnessing interleukin 2 (LI-2) family power in fish; Study of rainbow trout IL-2, IL-15, IL-15L, and IL- 15Rα
2014 - 2018 主要組織適合遺伝子複合体(MHC)クラスII分子ペプチド積載機構の分子進化の解明

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論文 (92件)：

Peter Riederer, Sabrina Strobel, Toshiharu Nagatsu, Hirohisa Watanabe, Xiqun Chen, Peter-Andreas Löschmann, Jeswinder Sian-Hulsmann, Wolfgang H Jost, Thomas Müller, Johannes M Dijkstra, et al. Levodopa treatment: impacts and mechanisms throughout Parkinson's disease progression. Journal of neural transmission (Vienna, Austria : 1996). 2025
Jackson G Schumacher, Xinyuan Zhang, Eric A Macklin, Jian Wang, Armin Bayati, Johannes M Dijkstra, Hirohisa Watanabe, Michael A Schwarzschild, Marianna Cortese, Xuehong Zhang, et al. Baseline α-synuclein seeding activity and disease progression in sporadic and genetic Parkinson's disease in the PPMI cohort. medRxiv : the preprint server for health sciences. 2025
Johannes M. Dijkstra, Annette Kuehn, Eiji Sugihara, Yasuto Kondo. Exploring Fish Parvalbumins through Allergen Names and Gene Identities. Genes. 2024. 15. 10
Hirohisa Watanabe, Johannes M Dijkstra, Toshiharu Nagatsu. Parkinson's Disease: Cells Succumbing to Lifelong Dopamine-Related Oxidative Stress and Other Bioenergetic Challenges. International journal of molecular sciences. 2024. 25. 4
Johannes M Dijkstra, Toshiharu Nagatsu. The Life and Science of Professor Tsuneko Okazaki, and her time at Fujita Health University. Fujita medical journal. 2024. 10. 1. 1-7

講演・口頭発表等 (28件)：

Extreme allelic MHC class I diversification in bony fish: evolutionary and structural perspectives of the salmonid example
(Polymorphic Immune Molecules and Their Functional Diversity Across Species 2025)
Major Histocompatibility Complex (MHC) molecules in fish: the origin of the MHC system
(ISDCI (International Society of Developmental & Compartive Immunology) Seminar series 2025)
Exploring Fish Parvalbumins through Allergen Names, Gene Identities, and IgE Reactivites
(EAACI (European Academy of Allergy and Clinical Immunology) Congress 2025, Glasgow, Scotland, 2025 2025)
The evolution of interleukins 2, 15, and 15-like, an ancient family of cytokines involved in lymphocyte activation
(Seminar, Institute for Life and Medical Sciences, Kyoto University 2022)
Deep Evolution of MHC Molecules
(Seminar at Institute of Immunology and Infection Research, University of Edinburgh, UK 2022)

学位 (1件)：

Ph.D. (Utrecht University, Holland)

経歴 (10件)：

2020/04 - 現在 Fujita Health University Research Promotion and Support Headquarters
2020/04 - 現在藤田医科大学総合医科学研究所准教授
2014 - 2020/03 藤田保健衛生大学総合医科学研究所医高分子学研究部門講師
2004 - 2014 , Fujita Health University, Institute for Comprehensive Medical Science, Division of Biomedical Polymer Science Assistant Professor
2008 - 2010 藤田保健衛生大学助教

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受賞 (4件)：

2025/06 - Advisory Panel of IJMS (InternationalJournal of Molecular Sciences) Highly Cited Paper of IJMS in 2024 Paper title: Parkinson’s Disease: Cells Succumbing to Lifelong Dopamine-Related Oxidative Stress and Other Bioenergetic Challenge. Authors: Hirohisa Watanabe, Johannes M. Dijkstra, Toshiharu Nagatsu
2022/05 - Editors of Toxins (MDPI) Editor's Choice Article Bitiscetin-3, a Novel C-Type Lectin-like Protein Cloned from the Venom Gland of the Viper Bitis arietans, Induces Platelet Agglutination and Inhibits Binding of Von Willebrand Factor to Collagen. Nashimoto Y, Matsushita F, Dijkstra JM, Nakamura Y, Akiyama H, Hamako J, Morita T, Araki S, Matsui T. Toxins (Basel). 2022 Mar 25;14(4):236. doi: 10.3390/toxins14040236.
2022/02 - PNAS Editors Paper selection for highlighting In This Issue (https://www.pnas.org/doi/10.1073/iti5121118) and Commentary article (doi: 10.1073/pnas.2122079119). Discovery of an ancient MHC category with both class I and class II features. Okamura K, Dijkstra JM, Tsukamoto K, Grimholt U, Wiegertjes GF, Kondow A, Yamaguchi H, Hashimoto K. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2108104118. doi: 10.1073/pnas.2108104118.
2021/08 - The Japanese Association for Developmental and Comparative Immunology Furuta Excellent Paper Award Ancient Cytokine Interleukin 15-Like (IL-15L) Induces a Type 2 Immune Response

所属学会 (4件)：

American Association for the Advancement of Science (AAAS) , The Molecular Biology Society of Japan (MBSJ) , The Japanese Association for Developmental & Comparative Immunology (JADCI) , Japanese Society for Immunology (JSI)

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