2019 - 2020 Nano-imaging of intracellular structures and membrane trafficking in the extending neuronal growth cone
2017 - 2019 神経成長・再生を誘導する成長円錐のアクチン依存性エンドサイトーシス
2015 - 2018 神経成長円錐のアクチン再編を伴う小胞輸送機構
2017 - 神経突起伸長の駆動力を生み出す先端構造の超解像ナノイメージング
2012 - 2015 神経成長における極長鎖脂肪酸伸長酵素の役割
2010 - 2012 成長円錐における神経成長関連蛋白質群の機能
2005 - 2010 成長円錐のシナプス形成に関与するCa^<2+>センサーの探索と機能解析
全件表示
論文 (20件):
Motohiro Nozumi, Yuta Sato, Miyako Nishiyama-Usuda, Michihiro Igarashi. Identification of z-axis filopodia in growth cones using super-resolution microscopy. Journal of Neurochemistry. 2024
Atsuko Honda, Motohiro Nozumi, Yasuyuki Ito, Rie Natsume, Asami Kawasaki, Fubito Nakatsu, Manabu Abe, Haruki Uchino, Natsuki Matsushita, Kazutaka Ikeda, et al. Very-long-chain fatty acids are crucial to neuronal polarity by providing sphingolipids to lipid rafts. Cell reports. 2023. 113195-113195
Masayasu Okada, Yosuke Kawagoe, Toshiyuki Takasugi, Motohiro Nozumi, Yasuyuki Ito, Hayato Fukusumi, Yonehiro Kanemura, Yukihiko Fujii, Michihiro Igarashi. JNK1-Dependent Phosphorylation of GAP-43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Neurochemical research. 2022. 47. 9. 2668-2682
Masayasu Okada, Yosuke Kawagoe, Toshiyuki Takasugi, Motohiro Nozumi, Yasuyuki Ito, Hayato Fukusumi, Yonehiro Kanemura, Yukihiko Fujii, Michihiro Igarashi. Correction to: JNK1-Dependent Phosphorylation of GAP-43 Serine 142 is a Novel Molecular Marker for Axonal Growth. Neurochemical research. 2022. 47. 9. 2683-2683
Masayasu Okada, Yosuke Kawagoe, Yuta Sato, Motohiro Nozumi, Yuya Ishikawa, Atsushi Tamada, Hiroyuki Yamazaki, Yuko Sekino, Yonehiro Kanemura, Yohei Shinmyo, et al. Phosphorylation of GAP-43 T172 is a molecular marker of growing axons in a wide range of mammals including primates. Molecular brain. 2021. 14. 1. 66-66
M. Nozumi, M. Igarashi. Membrane retrieval coincides with the filopodia formation in the neuronal growth cone. MOLECULAR BIOLOGY OF THE CELL. 2014. 25
A. Kawasaki, M. Nozumi, K. Takeuchi, N. Yoshioka, M. Igarashi. The in vivo GAP-43 phosphorylation sites involved in axon growth or regeneration. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 56-56
Visualization of various organelle dynamics by super-resolution shadow imaging of intracellular space.
(第45回日本神経科学大会、第65回日本神経化学会大会、第32回日本神経回路学会大会合同大会 シンポジウム「脳の細胞内外の構造を超解像可視化技術で明らかにする」 2022)
Actin reorganization and plasma membrane trafficking in three-dimensional space of nerve growth cones.
(第126回日本解剖学会総会・全国学術集会シンポジウム「神経分岐パターンを肉眼解剖学・発生学・生理学から再考する」 2021)
Super-resolution shadow imaging of intracellular space reveals various organelle dynamics in living cells.
(第63回日本神経化学会 シンポジウム「超解像度顕微鏡から見た新しい神経系の分子像」 2020)
New relationships between F actin organization and membrane trafficking in the growth cone revealed by SIM.
(Neuroscience 2018, Society for Neuroscience ” New observations in neuroscience using superresolution microscopy” 2018)