文献

J-GLOBAL ID：201102247019242868   整理番号：11A0809476

ヒト脂肪組織における脂肪分解遺伝子の貯蔵脂肪特異的発現-CES1発現,トリグリセリドリパーゼ活性および肥満症間の関連

Depot-Specific Expression of Lipolytic Genes in Human Adipose Tissues -Association Among CES1 Expression, Triglyceride Lipase Activity and Adiposity

著者 (26件)： NAGASHIMA Shuichi (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  YAGYU Hiroaki (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  TAKAHASHI Nirei (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  KURASHINA Tomoyuki (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  TAKAHASHI Manabu (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  TSUCHITA Takeshi (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  TAZOE Fumiko (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  WANG Xiao Li (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  BAYASGALAN Tumenbayar (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  SATO Naoko (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  OKADA Kenta (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  NAGASAKA Shoichiro (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.) ,  GOTOH Takaya (Div. of Human Genetics, Center for Community Medicine, Jichi Medical Univ.) ,  KOJIMA Masayuki (Dep. of Surgery, Jichi Medical Univ.) ,  HYODO Masanobu (Dep. of Surgery, Jichi Medical Univ.) ,  HORIE Hisanaga (Dep. of Surgery, Jichi Medical Univ.) ,  HOSOYA Yoshinori (Dep. of Surgery, Jichi Medical Univ.) ,  OKADA Masaki (Dep. of Surgery, Jichi Medical Univ.) ,  YASUDA Yoshikazu (Dep. of Surgery, Jichi Medical Univ.) ,  FUJIWARA Hiroyuki (Dep. of Obstetrics and Gynecology, Jichi Medical Univ.) ,  OHWADA Michitaka (Dep. of Obstetrics and Gynecology, Jichi Medical Univ.) ,  IWAMOTO Sadahiko (Div. of Human Genetics, Center for Community Medicine, Jichi Medical Univ.) ,  SUZUKI Mitsuaki (Dep. of Obstetrics and Gynecology, Jichi Medical Univ.) ,  NAGAI Hideo (Dep. of Surgery, Jichi Medical Univ.) ,  NAGAI Hideo (Dep. of Surgery, Ibaraki Prefectural Central Hospital.) ,  ISHIBASHI Shun (Div. of Endocrinology and Metabolism, Diabetes Center, Dep. of Medicine, Jichi Medical Univ.)
資料名： Journal of Atherosclerosis and Thrombosis (Web)  (Journal of Atherosclerosis and Thrombosis (Web))
巻： 18  号： 3  ページ： 190-199 (J-STAGE)  発行年： 2011年 
JST資料番号： U0153A  ISSN： 1880-3873  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 目的:脂肪細胞の脂肪分解はホルモン感受性リパーゼ(LIPE)...

シソーラス用語： ヒト ,...
準シソーラス用語： mRNA発現 ,...

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分類 (3件)： 遺伝子発現  (EC02040Q) ,  代謝異常・栄養性疾患一般  (GD05010J) ,  酵素一般  (EB09010D)

引用文献 (50件)：

• 1) Boden G: Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes, 1997; 46: 3-10
• 2) Furuhashi M, Hotamisligil GS: Fatty acidbinding proteins: role in metabolic diseases and potential as drug targets. Nat Rev Drug Discov, 2008; 7: 489-503
• 3) Zechner R, Strauss JG, Haemmerle G, Lass A, Zimmermann R: Lipolysis: pathway under construction. Curr Opin Lipidol, 2005; 16: 333-340
• 4) Arner P, Langin D: The role of neutral lipases in human adipose tissue lipolysis. Curr Opin Lipidol, 2007; 18: 246-250
• 5) Holm C: Molecular mechanisms regulating hormonesen-sitive lipase and lipolysis. Biochem Soc Trans, 2003; 31: 1120-1124

タイトルに関連する用語 (10件)： ヒト ,  脂肪組織 ,  脂肪分解 ,  遺伝子 ,  貯蔵 ,  脂肪 ,  発現 ,  トリグリセリドリパーゼ ,  活性 ,  肥満症