2014 - 2017 Cellular and animal models of human CNV
2014 - 2015 ヒト染色体異常に基づく染色体改変モデルマウスの統合的解析
2012 - 2013 染色体工学を用いた精神疾患モデルマウスの統合的解析
2008 - 統合失調症候補遺伝子の神経系への影響を幹細胞からアプローチする
2008 - 精神疾患の神経発達学的研究
2008 - 遺伝子変異ES細胞を用いた精神疾患の神経発達学的研究
2006 - 2007 ES細胞の腫瘍原性における転写補助因子UTF1の役割
2007 - 精神疾患の神経発達学的研究
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論文 (26件):
Sawako Furukawa*, Jun Nomura* (contributed equally), HIroaki Hanafusa, Hiroko Maegawa, Toru Takumi. Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders. Autism Research. 2023. 16. 6. 1101-1110
Chia-Wen Lin, Dian E. Septyaningtrias, Hsu-Wen Chao, Mikiko Konda, Koji Atarashi, Kozue Takeshita, Kota Tamada, Jun Nomura, Yohei Sasagawa, Kaori Tanaka, et al. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model. Molecular Psychiatry. 2022. 27. 8. 3343-3354
Jun Nomura, Amila Zuko, Keiko Kishimoto, Hiroaki Mutsumine, Kazumi Fukatsu, Yoshiko Nomura, Xiaoxi Liu, Nobuhiro Nakai, Eiki Takahashi, Tsukasa Kouno, et al. Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability. BioRxiv. 2022
Yoshiko Nomura, Jun Nomura, Toru Nishikawa, Toru Takumi. Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV. BioRrxiv. 2021
Jun Nomura, Matthew Mardo, Toru Takumi. Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia. Journal of Neurochemistry. 2021. 159. 4. 647-659
Jun Nomura, Akifumi Kanda, Yusuke Sotomaru, Toru Takumi. Phenotypic analysis of a mouse model for 15q25.2-25.3 deletion syndrome. International Journal of Neuropsychopharmacology. 2016. 19. Suppl_1. 3-3
【Symposium】Autism in a Dish; Identification of risk factors using cellular models of neurodevelopmental disorders
(The 16th International Meeting of the Japanese Consortium for Autism Research, The CMX Symposium for Autism, 2023)
2008 - 2011 Johns Hopkins University School of Medicine Department of Psychiatry & Behavioral Sciences, USA, Postdoctoral fellow / Research fellow
2005 - 2008 埼玉医科大学 医学部 ゲノム医学研究センター 研究員
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受賞 (6件):
2023 - Journal of Neurochemistry (Wiley) Top Downloaded Article in Journal of Neurochemistry Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia
2022 - Neuroscience Research (Elsevier) Excellent Paper Award Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion.
2020/01 - Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences Excellent Poster Award
2014 - RIKEN BSI Riken BSI Hot Topics 2014 Genome Editing Tools for Neurobiology
2009 - International Congress on Schizophrenia Research (ICOSR), Young Investigator Program Award 2009, USA, A new cell model to study the mechanism of gene-environment interactions relevant to schizophrenia
2007 - 財団法人 細胞科学研究財団 育成助成 精神疾患の神経発達学的研究 -Neurodevelopmental study of schizophrenia-
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所属学会 (8件):
日本バイオインフォマティクス学会
, 日本生化学会
, 日本分子生物学会
, 日本神経化学会
, 日本神経科学学会
, 日本神経精神薬理学会
, International College of Neuropsychopharmacology
, Society for Neuroscience