2014 - 2017 Cellular and animal models of human CNV
2014 - 2015 ヒト染色体異常に基づく染色体改変モデルマウスの統合的解析
2012 - 2013 染色体工学を用いた精神疾患モデルマウスの統合的解析
2008 - 統合失調症候補遺伝子の神経系への影響を幹細胞からアプローチする
2008 - 精神疾患の神経発達学的研究
2008 - 遺伝子変異ES細胞を用いた精神疾患の神経発達学的研究
2006 - 2007 ES細胞の腫瘍原性における転写補助因子UTF1の役割
2007 - 精神疾患の神経発達学的研究
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論文 (26件):
Sawako Furukawa*, Jun Nomura* (contributed equally), HIroaki Hanafusa, Hiroko Maegawa, Toru Takumi. Germ-cell-specific transcriptome analysis illuminates the chromatin and ubiquitin pathway in autism spectrum disorders. Autism Research. 2023. 16. 6. 1101-1110
Chia-Wen Lin, Dian E. Septyaningtrias, Hsu-Wen Chao, Mikiko Konda, Koji Atarashi, Kozue Takeshita, Kota Tamada, Jun Nomura, Yohei Sasagawa, Kaori Tanaka, et al. A common epigenetic mechanism across different cellular origins underlies systemic immune dysregulation in an idiopathic autism mouse model. Molecular Psychiatry. 2022. 27. 8. 3343-3354
Jun Nomura, Amila Zuko, Keiko Kishimoto, Hiroaki Mutsumine, Kazumi Fukatsu, Yoshiko Nomura, Xiaoxi Liu, Nobuhiro Nakai, Eiki Takahashi, Tsukasa Kouno, et al. Autism in a dish: ES cell models of autism with copy number variations reveal cell-type-specific vulnerability. BioRxiv. 2022
Yoshiko Nomura, Jun Nomura, Toru Nishikawa, Toru Takumi. Reciprocal differentiation via GABAergic components and ASD-related phenotypes in hES with 1q21.1 CNV. BioRrxiv. 2021
Jun Nomura, Matthew Mardo, Toru Takumi. Molecular signatures from multi-omics of autism spectrum disorders and schizophrenia. Journal of Neurochemistry. 2021. 159. 4. 647-659
Jun Nomura, Akifumi Kanda, Yusuke Sotomaru, Toru Takumi. Phenotypic analysis of a mouse model for 15q25.2-25.3 deletion syndrome. International Journal of Neuropsychopharmacology. 2016. 19. Suppl_1. 3-3
【Symposium】Autism in a Dish; Identification of risk factors using cellular models of neurodevelopmental disorders
(The CMX Symposium for Autism, The 16th International Meeting of The Japanese Consortium for Autism Research 2023)
【Symposium】Identification of risk factors using cellular models of neurodevelopmental disorders
(The 64th Annual Meeting of the Japanese Society of Neuropathology, The 66th Annual Meeting of the Japanese Society for Neurochemistry 2023)
【Symposium】Brain Science of Neurodevelopmental Disorders
(ASCAPAP 2023 [The 11th Congress of The Asian Society for Child and Adolescent Psychiatry and Allied Professions] 2023)
【Seminar】ES cell models of autism with copy number variations reveal cell-type-specific vulnerability.
(The 1st NSN (Neuroscience Network in Kobe) Research Seminar 2023)
2008 - 2011 Johns Hopkins University School of Medicine Department of Psychiatry & Behavioral Sciences, USA, Postdoctoral fellow / Research fellow
2005 - 2008 埼玉医科大学 医学部 ゲノム医学研究センター 研究員
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受賞 (6件):
2023 - Top Downloaded Article in Journal of Neurochemistry (Wiley)
2022 - Neuroscience Research (Elsevier) Excellent Paper Award Transcriptome analysis of human neural cells derived from isogenic embryonic stem cells with 16p11.2 deletion.
2020/01 - Takeda Science Foundation, The 10th Takeda Science Foundation International Symposium on PharmaSciences Excellent Poster Award
2014 - RIKEN BSI Riken BSI Hot Topics 2014 Genome Editing Tools for Neurobiology
2009 - International Congress on Schizophrenia Research (ICOSR), Young Investigator Program Award 2009, USA, A new cell model to study the mechanism of gene-environment interactions relevant to schizophrenia
2007 - 財団法人 細胞科学研究財団 育成助成 精神疾患の神経発達学的研究 -Neurodevelopmental study of schizophrenia-
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所属学会 (8件):
日本バイオインフォマティクス学会
, 日本生化学会
, 日本分子生物学会
, 日本神経化学会
, 日本神経科学学会
, 日本神経精神薬理学会
, International College of Neuropsychopharmacology
, Society for Neuroscience