文献

J-GLOBAL ID：201202236660043471   整理番号：12A0338799

2型糖尿病の日本人被験者でのTNF-α C-857Tとアディポネクチン G+276T遺伝子多型の組合わせに依存するインシュリン抵抗性と脂肪肝への感受性の差異

Different Susceptibility to Insulin Resistance and Fatty Liver Depending on the Combination of TNF-α C-857T and Adiponectin G+276T Gene Polymorphisms in Japanese Subjects with Type 2 Diabetes

著者 (15件)： OHARA Mio (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  MAESAWA Chihaya (Div. of Bioscience, Dep. of Tumor Biology, Center for Advanced Medical Sci., Iwate Medical Univ. School of Medicine) ,  TAKEBE Noriko (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  TAKAHASHI Toru (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  YAMASHINA Mitsuhiro (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  ONO Mitsutaka (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  MATSUI Mizue (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  SASAI Takayoshi (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  HONMA Hiroyuki (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  NAGASAWA Kan (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  FUJIWARA Fumikado (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  KAJIWARA Takashi (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  TANEICHI Haruhito (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  TAKAHASHI Kazuma (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine) ,  SATOH Jo (Div. of Diabetes and Metabolism, Dep. of Internal Medicine, Iwate Medical Univ. School of Medicine)
資料名： Tohoku Journal of Experimental Medicine  (Tohoku Journal of Experimental Medicine)
巻： 226  号： 2  ページ： 161-169 (J-STAGE)  発行年： 2012年 
JST資料番号： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： TNF-α遺伝子のC-857Tプロモーター多型は肥満性の2型...

シソーラス用語： ヒト ,...
準シソーラス用語： *インシュリン非依存性糖尿病 ,...

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分類 (1件)： 代謝異常・栄養性疾患一般  (GD05010J)

引用文献 (29件)：

• DACHUN, X. Sensitivity and specificity of the ankle-brachial index to diagnose peripheral artery disease : a structured review. Vasc. Med. 2010, 15, 361-369
• DATE, Y. Identification of a genetic risk factor for systemic juvenile rheumatoid arthritis in the 5'-flanking region of the TNF-alpha gene and HLA genes. Arthritis Rheum. 1999, 42, 2577-2582
• FERNANDEZ-REAL, J. M. The TNF-alpha gene Nco I polymorphism influences the relationship among insulin resistance, percent body fat, and increased serum leptin levels. Diabetes. 1997, 46, 1468-1472
• GONZALEZ-SANCHEZ, J. L. Interaction of the -308G/A promoter polymorphism of the tumor necrosis factor-alphagene with single-nucleotide polymorphism 45 of the adiponectingene : effect on serum adiponectin concentrations in a Spanish population. Clin. Chem. 2006, 52, 97-103
• GUSTAFSON, B. Inflamed adipose tissue : a culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2007, 27, 2276-2283

タイトルに関連する用語 (11件)： 2型糖尿病 ,  日本人 ,  被験者 ,  TNF-α ,  アディポネクチン ,  遺伝子多型 ,  組合わせ ,  インシュリン抵抗性 ,  脂肪肝 ,  感受性 ,  差異