文献

J-GLOBAL ID：201302210746327365   整理番号：12A1796011

進行大腸癌の日本人患者におけるファーストラインFOLFIRI療法の有効性とABCC2遺伝子型の関連

Association of ABCC2 Genotype with Efficacy of First-line FOLFIRI in Japanese Patients with Advanced Colorectal Cancer

著者 (12件)： AKIYAMA Yuko (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  AKIYAMA Yuko (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.) ,  FUJITA Ken-ichi (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  FUJITA Ken-ichi (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.) ,  ISHIDA Hiroo (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SUNAKAWA Yu (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  YAMASHITA Keishi (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  KAWARA Kaori (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  MIWA Keisuke (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SAJI Shigehira (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SASAKI Yasutsuna (Dep. of Medical Oncology, International Medical Center-Comprehensive Cancer Center, Saitama Medical Univ.) ,  SASAKI Yasutsuna (Project Res. Lab., Res. Center for Genomic Medicine, Saitama Medical Univ.)
資料名： Drug Metabolism and Pharmacokinetics  (Drug Metabolism and Pharmacokinetics)
巻： 27  号： 3  ページ： 325-335 (J-STAGE)  発行年： 2012年 
JST資料番号： X0758A  ISSN： 1347-4367  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： この探査的後ろ向き研究では,日本人進行大腸癌患者においてファ...

シソーラス用語： ヒト ,...
準シソーラス用語： ABCC2遺伝子

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分類 (2件)： 消化器の腫よう  (GH04000D) ,  腫ようの薬物療法  (GE03032C)

物質索引 (3件)： フルオロウラシル ,  レボホリナートカルシウム ,  塩酸イリノテカン

引用文献 (41件)：

• 1) Kudoh, S., Fujiwara, Y., Takada, Y., Yamamoto, H., Kinoshita, A., Ariyoshi, Y., Furuse, K. and Fukuoka, M.: Phase II study of irinotecan combined with cisplatin in patients with previously untreated small-cell lung cancer. West Japan Lung Cancer Group. J. Clin. Oncol., 16: 1068–1074 (1998).
• 2) Negoro, S., Fukuoka, M., Masuda, N., Takada, M., Kusunoki, Y., Matsui, K., Takifuji, N., Kudoh, S., Niitani, H. and Taguchi, T.: Phase I study of weekly intravenous infusions of CPT-11, a new derivative of camptothecin, in the treatment of advanced non-small-cell lung cancer. J. Natl. Cancer Inst., 83: 1164–1168 (1991).
• 3) Rougier, P., Van Cutsem, E., Bajetta, E., Niederle, N., Possinger, K., Labianca, R., Navarro, M., Morant, R., Bleiberg, H., Wils, J., Awad, L., Herait, P. and Jacques, C.: Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer. Lancet, 352: 1407–1412 (1998).
• 4) Sparreboom, A., Fujita, K. and Zamboni, W. C.: Topoisomerase I-Targeting Drugs. In Chabner, B. A. and Longo, D. L. (eds.): <i>Cancer Chemotherapy and Biotherapy Principles and Practice</i>, Philadelphia: Lippincott Williams & Wilkins, 2010, pp. 342–355.
• 5) Nozawa, T., Minami, H., Sugiura, S., Tsuji, A. and Tamai, I.: Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms. Drug Metab. Dispos., 33: 434–439 (2005).

タイトルに関連する用語 (6件)： 進行大腸癌 ,  日本人 ,  患者 ,  FOLFIRI療法 ,  有効性 ,  ABCC2遺伝子