文献

J-GLOBAL ID：201302240620311621   整理番号：13A0364059

α-リポ酸は急性冠症候群の患者においてアルデヒドデヒドロゲナーゼ-2活性の増加により酸化ストレスを改善する

Alpha-Lipoic Acid Ameliorates Oxidative Stress by Increasing Aldehyde Dehydrogenase-2 Activity in Patients with Acute Coronary Syndrome

著者 (10件)： LI Rui-jian (Dep. of Emergency, Qilu Hospital of Shandong Univ.) ,  JI Wen-qing (Dep. of Emergency, Qilu Hospital of Shandong Univ.) ,  JI Wen-qing (Key Lab. of Cardiovascular Remodeling and Function Res. affiliated to Chinese Ministry of Education and Chinese ...) ,  PANG Jiao-jiao (Dep. of Emergency, Qilu Hospital of Shandong Univ.) ,  PANG Jiao-jiao (Key Lab. of Cardiovascular Remodeling and Function Res. affiliated to Chinese Ministry of Education and Chinese ...) ,  WANG Jia-li (Dep. of Emergency, Qilu Hospital of Shandong Univ.) ,  CHEN Yu-guo (Dep. of Emergency, Qilu Hospital of Shandong Univ.) ,  CHEN Yu-guo (Key Lab. of Cardiovascular Remodeling and Function Res. affiliated to Chinese Ministry of Education and Chinese ...) ,  ZHANG Yun (Key Lab. of Cardiovascular Remodeling and Function Res. affiliated to Chinese Ministry of Education and Chinese ...) ,  ZHANG Yun (Dep. of Cardiology, Qilu Hospital of Shandong Univ.)
資料名： Tohoku Journal of Experimental Medicine  (Tohoku Journal of Experimental Medicine)
巻： 229  号： 1  ページ： 45-51 (J-STAGE)  発行年： 2012年 
JST資料番号： G0649A  ISSN： 0040-8727  CODEN： TJEMAO  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： アルデヒドデヒドロゲナーゼ-2(ALDH2)はエタノール代謝...

シソーラス用語： ヒト ,...
準シソーラス用語： *急性冠症候群 ,...

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分類 (2件)： 循環系疾患の薬物療法  (GJ05020M) ,  酵素製剤・酵素阻害剤の臨床への応用  (GW21020H)

物質索引 (1件)： α-リポ酸

引用文献 (27件)：

• Azumi, H., Inoue, N., Ohashi, Y., Terashima, M., Mori, T., Fujita, H., Awano, K., Kobayashi, K., Maeda, K., Hata, K., Shinke, T., Kobayashi, S., Hirata, K., Kawashima, S., Itabe, H., Hayashi, Y., Imajoh-Ohmi, S., Itoh, H. & Yokoyama, M. (2002) Superoxide generation in directional coronary atherectomy specimens of patients with angina pectoris: important role of NAD(P)H oxidase. <i>Arterioscler. Thromb. Vasc. Biol</i>., <b>22</b>, 1838-1844.
• Benndorf, R.A., Schwedhelm, E., Gnann, A., Taheri, R., Kom, G., Didié, M., Steenpass, A., Ergün, S. & Böger, R.H. (2008) Isoprostanes inhibit vascular endothelial growth factorinduced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis. <i>Circ. Res</i>., <b>103</b>, 1037-1046.
• Bian, Y., Chen, Y.G., Xu, F., Xue, L., Ji, W.Q. & Zhang, Y. (2010) The polymorphism in aldehyde dehydrogenase-2 gene is associated with elevated plasma levels of high-sensitivity C-reactive protein in the early phase of myocardial infarction. <i>Tohoku J. Exp. Med</i>., <b>221</b>, 107-112.
• Bosron, W.F. & Li, T.K. (1986) Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. <i>Hepatology</i>, <b>6</b>, 502-510.
• Channon, K.M. (2002) Oxidative stress and coronary plaque stability. Arterioscler. Thromb. Vasc. Biol., 22, 1751-1752.

タイトルに関連する用語 (6件)： α-リポ酸 ,  急性冠症候群 ,  患者 ,  アルデヒドデヒドロゲナーゼ ,  活性 ,  酸化ストレス