文献

J-GLOBAL ID：201302263457272575   整理番号：13A0527874

がん治療を目的とする標的ポリカチオンリポソームを用いた低分子干渉RNAの全身デリバリー

Systemic Delivery of Small Interfering RNA by Use of Targeted Polycation Liposomes for Cancer Therapy

著者 (12件)： KENJO Eriya (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  ASAI Tomohiro (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  YONENAGA Norihito (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  ANDO Hidenori (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  ISHII Takayuki (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  HATANAKA Kentaro (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  SHIMIZU Kosuke (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka) ,  URITA Yugo (Dep. of Frontier Materials, Graduate School of Engineering, Nagoya Inst. of Technol.) ,  DEWA Takehisa (Dep. of Frontier Materials, Graduate School of Engineering, Nagoya Inst. of Technol.) ,  NANGO Mamoru (Dep. of Frontier Materials, Graduate School of Engineering, Nagoya Inst. of Technol.) ,  TSUKADA Hideo (PET Center, Central Res. Lab., Hamamatsu Photonics K.K.) ,  OKU Naoto (Dep. of Medical Biochemistry, School of Pharmaceutical Sciences, Univ. of Shizuoka)
資料名： Biological and Pharmaceutical Bulletin  (Biological and Pharmaceutical Bulletin)
巻： 36  号： 2  ページ： 287-291 (J-STAGE)  発行年： 2013年 
JST資料番号： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 環状(Cys-Arg-Gly-Asp-d-Phe)ペプチドに...

シソーラス用語： ヒト ,...
準シソーラス用語： ポリカチオン ,...

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分類 (3件)： 皮膚の腫よう  (GF04000X) ,  腫ようの実験的治療  (GE02040Y) ,  遺伝子発現  (EC02040Q)

引用文献 (18件)：

• 1) Hutvágner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science, 297, 2056–2060 (2002).
• 2) Davis ME, Zuckerman JE, Choi CH, Seligson D, Tolcher A, Alabi CA, Yen Y, Heidel JD, Ribas A. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature, 464, 1067–1070 (2010).
• 3) Chen SH, Zhaori G. Potential clinical applications of siRNA technique: benefits and limitations. Eur. J. Clin. Invest., 41, 221–232 (2011).
• 4) Pecot CV, Calin GA, Coleman RL, Lopez-Berestein G, Sood AK. RNA interference in the clinic: challenges and future directions. Nat. Rev. Cancer, 11, 59–67 (2011).
• 5) Yamazaki Y, Nango M, Matsuura M, Hasegawa Y, Hasegawa M, Oku N. Polycation liposomes, a novel nonviral gene transfer system, constructed from cetylated polyethylenimine. Gene Ther., 7, 1148–1155 (2000).

タイトルに関連する用語 (5件)： がん治療 ,  標的 ,  カチオンリポソーム ,  低分子干渉RNA ,  全身デリバリー