文献

J-GLOBAL ID：201302269273789450   整理番号：13A0510384

BCL-XLおよびMEK阻害の併用による合成致死的相互作用はKRAS変異体癌モデルにおいて腫瘍の退縮を促進する

Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models

著者 (27件)： CORCORAN Ryan B. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  CORCORAN Ryan B. (Dep. of Medicine, Harvard Medical School, Boston, MA 02115, USA) ,  CHENG Katherine A. (Dana Farber Cancer Inst., Boston, MA 02114, USA) ,  HATA Aaron N. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  HATA Aaron N. (Dep. of Medicine, Harvard Medical School, Boston, MA 02115, USA) ,  FABER Anthony C. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  FABER Anthony C. (Dep. of Medicine, Harvard Medical School, Boston, MA 02115, USA) ,  EBI Hiromichi (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  EBI Hiromichi (Dep. of Medicine, Harvard Medical School, Boston, MA 02115, USA) ,  COFFEE Erin M. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  COFFEE Erin M. (Div. of Gastroenterology, Tufts Medical Center, Boston, MA 02111, USA) ,  GRENINGER Patricia (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  BROWN Ronald D. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  GODFREY Jason T. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  COHOON Travis J. (Dana Farber Cancer Inst., Boston, MA 02114, USA) ,  SONG Youngchul (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  LIFSHITS Eugene (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  HUNG Kenneth E. (Div. of Gastroenterology, Tufts Medical Center, Boston, MA 02111, USA) ,  SHIODA Toshi (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  DIAS-SANTAGATA Dora (Dep. of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA) ,  SINGH Anurag (Boston Univ., Boston, MA 02118, USA) ,  SETTLEMAN Jeffrey (Genentech, Inc., South San Francisco, CA 94080, USA) ,  BENES Cyril H. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  MINO-KENUDSON Mari (Dep. of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02115, USA) ,  WONG Kwok-kin (Dana Farber Cancer Inst., Boston, MA 02114, USA) ,  ENGELMAN Jeffrey A. (Massachusetts General Hospital Cancer Center, Boston, MA 02129, USA) ,  ENGELMAN Jeffrey A. (Dep. of Medicine, Harvard Medical School, Boston, MA 02115, USA)
資料名： Cancer Cell  (Cancer Cell)
巻： 23  号： 1  ページ： 121-128  発行年： 2013年01月14日 
JST資料番号： W1844A  ISSN： 1535-6108  資料種別： 逐次刊行物 (A)
発行国： オランダ (NLD)  言語： 英語 (EN)

タイトルに関連する用語 (11件)： Bcl-XL ,  MEK ,  阻害 ,  併用 ,  相互作用 ,  KRAS ,  変異体 ,  癌 ,  モデル ,  腫瘍 ,  促進