原田浩

ハラダヒロシ | Harada Hiroshi

所属機関・部署：
職名：教授

研究分野 (6件)：分子生物学 , 細胞生物学 , 病態医化学 , 放射線科学 , ゲノム生物学 , 腫瘍生物学

競争的資金等の研究課題 (36件)：

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論文 (159件)：

Tatsuyuki Sato, Takayuki Isagawa, Toshinaru Kawakami, Sosuke Hosokawa, Masamichi Ito, Daigo Sawaki, Shigeru Sato, Yu Nakagama, Kazutoshi Ono, Ariunbold Chuluun-Erdene, et al. The REFLEX system enables in vivo identification of perivascular angiogenic macrophages in the heart. J Biol Chem. 2025
Yoshifumi Ueda, Shigeki Kiyonaka, Laura M. Selfors, Keisuke Inoue, Hiroshi Harada, Tomohiro Doura, Kunishige Onuma, Makoto Uchiyama, Ryuhei Kurogi, Yuji Yamada, et al. Intratumour oxidative hotspots provide a niche for cancer cell dissemination. Nature Cell Biology. 2025
Peter W T Lee, Minoru Kobayashi, Takakuni Dohkai, Itsuki Takahashi, Takumi Yoshida, Hiroshi Harada. 2-oxoglutarate-dependent Dioxygenases (2-OGDDs) as Oxygen Sensors: Their Importance in Health and Disease. The Journal of Biochemistry. 2024
Gouki Kambe, Minoru Kobayashi, Hiroshi Ishikita, Sho Koyasu, Ester M. Hammond, Hiroshi Harada. ZBTB7A forms a heterodimer with ZBTB2 and inhibits ZBTB2 homodimerization required for full activation of HIF-1. Biochemical and Biophysical Research Communications. 2024. 733. 150604-150604
Huiying Mu, Shuai Shao, Bingquan Wu, Koji Miki, Minoru Kobayashi, Hiroshi Harada, Kouichi Ohe. Fast tumor imaging using pH-responsive aggregation of cyanine dyes with rapid clearance. Sensors and Actuators B: Chemical. 2024. 413. 135876-135876

MISC (24件)：

特許 (9件)：

書籍 (5件)：

放射線治療学改訂7版
南山堂 2023 ISBN:9784525270971
がん・放射線療法改訂第8版
2023
Molecularly based Chemoradiotherapy and High-Precision Radiotherapy. Tan D, Lynch H (eds).
Lippincott Williams & Milkins. 2012
Protein Transduction Domain-mediated Delivery of Anti-cancer Drugs and Proteins. Lu Y and Mahato RI (eds). Pharmaceutical Perspectives of Cancer Therapeutics.
Springer 2009
Combination of Antimetabolites and Ionizing Radiation. Medical Radiology: Radiation Oncology, Multimodal Concepts for Integration of Cytotoxic Drugs.
Springer 2006

講演・口頭発表等 (171件)：

The Impact of Hypoxia on Tumor Recurrence and Genome Instability
(UCLA-KU-AS Asia-Pan Pacific Meeting 2025)
The Importance of Hypoxia in Tumor Recurrence and Cancer Genome Heterogeneity
(Seoul National University Seminar 2025)
がんの低酸素応答機構の理解と利用
(第14回生理化学ユニットシンポジウム 2024)
がんを知り尽くそう
(Qカフェ 2024)
My interactions with NTU people and my research
(Japan-Taiwan Biotech Association annual symposium 2024)

学位 (1件)：

受賞 (13件)：

2023/11 - 日本放射線影響学会 JRRS Distinguished Scientist Award がんの放射線抵抗性と悪性化を導く低酸素応答機構に関する研究
2023/06 - (一般社団法人)大阪ニュークリアサイエンス協会大阪ニュークリアサイエンス協会賞
2022/12 - (公財)日本放射線腫瘍学会阿部賞
2018/11 - Journal of Radiation Research JRR Terasima Award Hypoxia-inducible factor 1-mediated characteristic features of cancer cells for tumor radioresistance
2014/10 - 日本放射線腫瘍学会第12回優秀教育講演賞放射線腫瘍学における"がん幹細胞"と"低酸素"

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原田 浩