研究者
J-GLOBAL ID:201401001576977454   更新日: 2021年09月20日

河原 真大

Kawahara Masahiro
所属機関・部署:
職名: 講師
研究分野 (1件): 血液、腫瘍内科学
競争的資金等の研究課題 (2件):
  • 2019 - 2022 NUDT15遺伝子型に基づき個人に最適化された安全かつ有効的なチオプリンによる免疫調節療法の開発
  • 2019 - 2022 急性白血病におけるスーパーエンハンサーを介した転写因子ネットワーク異常の解明
論文 (46件):
  • Yoshihiro Yokota, Osamu Inatomi, Minami Nakagawa, Kazuki Kakuda, Kousuke Hiroe, Shigeki Sakai, Rie Osaki, Masaki Iwasa, Masahiro Kawahara, Katsuyuki Kito, et al. Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy. Internal Medicine. 2021. 60. 16. 2663-2666
  • Akira Andoh, Masahiro Kawahara, Takayuki Imai, Goichi Tatsumi, Osamu Inatomi, Yoichi Kakuta. Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease. Journal of Gastroenterology. 2021
  • Yoshihiko Sugitani, Ryo Inoue, Osamu Inatomi, Atsushi Nishida, So Morishima, Takayuki Imai, Masahiro Kawahara, Yuji Naito, Akira Andoh. Mucosa-associated gut microbiome in Japanese patients with functional constipation. Journal of Clinical Biochemistry and Nutrition. 2021. 68. 2. 187-192
  • T. Imai, M. Kawahara, G. Tatsumi, N. Yamashita, A. Nishishita-Asai, O. Inatomi, A. Masamune, Y. Kakuta, A. Andoh. Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15R138C Knock-In Mice. Cellular and Molecular Gastroenterology and Hepatology. 2021. 12. 1. 335-337
  • Masaki Murata, Osam Inatomi, Katsuhiro Ono, Takayuki Imai, Masaki Iwasa, Masahiro Kawahara, Katsuyuki Kito, Akira Andoh. A case of life-threatening small intestinal bleeding accompanied by lower coagulation factor XIII activity. Clinical Journal of Gastroenterology. 2020. 13. 6. 1178-1182
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MISC (8件):
  • Kazuhisa Chonabayashi, Masahiro Kawahara, Akira Watanabe, Masahiro Nakamura, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida. Ips Technology Revealed the Genetic and Functional Diversity Present in a Secondary AML Patient. BLOOD. 2016. 128. 22
  • Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa, Norimitsu Kadowaki, Akifumi Takaori-Kondo, Shinya Yamanaka, Yoshinori Yoshida. Patient-Specific Induced Pluripotent Stem Cells Recapitulate the Maturation Defect of Myelodysplastic Syndromes. BLOOD. 2014. 124. 21
  • Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Sumie Fujii, Ryusuke Yamamoto, Masakatsu Hishizawa, Akifumi Takaori-Kondo. The Pharmacological Inhibition of KDM1A Displays Preclinical Efficacy in AML and MDS By Inducing Myelomonocytic Differentiation. BLOOD. 2014. 124. 21
  • Ujunwa C. Okoye-Okafor, Laura Barreyro, Mario Pujato, Heng Rui Wang, Boris Bartholdy, Britta Will, Tihomira I. Todorova, Masahiro Kawahara, Bruce Woolcock, Andras Fiser, et al. Characterization of a novel protein-coding gene named TIHL (Translocated in Hodgkin's Lymphoma). CANCER RESEARCH. 2014. 74. 19
  • Ujunwa Cynthia Okoye-Okafor, Boris Bartholdy, Bruce Woolcock, Masahiro Kawahara, Tihomira I. Todorova, Randy D. Gascoyne, Christian Steidl, Ulrich Steidl. Identification of a Novel Protein-Coding Gene (TIHL) and Its Functional Relevance in Myeloid Cells. BLOOD. 2012. 120. 21
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特許 (1件):
  • リシン構造を有するlsd1選択的阻害薬
学位 (1件):
  • 医学博士 (京都大学)
経歴 (2件):
  • 2017/03 - 現在 滋賀医科大学 内科学講座(血液内科) 講師
  • 2016/04 - 2017/02 滋賀医科大学 内科学講座(血液内科) 学内講師
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