研究者
J-GLOBAL ID:201401071137439690   更新日: 2024年01月31日

丹羽 明

Niwa Akira
所属機関・部署:
研究分野 (1件): 血液、腫瘍内科学
競争的資金等の研究課題 (9件):
  • 2020 - 2023 新規Epo抵抗性因子の探索と分子機序の解明:赤芽球分化・増殖と脂質代謝の関連性
  • 2017 - 2019 骨オルガノイドの創成とその骨疾患研究への応用
  • 2016 - 2019 内在性変異導入分子による白血病クローン多様性獲得機構の解明
  • 2014 - 2017 腫瘍血管新生の機序解明と新規治療開発を目的とした血管芽腫原因遺伝子の探索
  • 2014 - 2016 細胞内代謝と微小環境の制御による、ヒトES・iPS細胞由来造血幹細胞の維持増幅
全件表示
論文 (79件):
  • Jingxin Wang, Norikazu Saiki, Ayako Tanimura, Takafumi Noma, Akira Niwa, Tastutoshi Nakahata, Megumu K Saito. UK-5099, a mitochondrial pyruvate carrier inhibitor, recovers impaired neutrophil maturation caused by AK2 deficiency in human pluripotent stem cell models. Biochemical and biophysical research communications. 2023. 687. 149211-149211
  • Naoya Kase, Yohko Kitagawa, Akihiro Ikenaka, Akira Niwa, Megumu K. Saito. A concise in vitro model for evaluating interactions between macrophage and skeletal muscle cells during muscle regeneration. Frontiers in Cell and Developmental Biology. 2023. 11
  • Akihiro Ikenaka, Yohko Kitagawa, Michiko Yoshida, Chuang-Yu Lin, Akira Niwa, Tatsutoshi Nakahata, Megumu K Saito. SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis. Life science alliance. 2023. 6. 3
  • Takahiro Hayashi, Naoko Yano, Kengo Kora, Atsushi Yokoyama, Kanako Maizuru, Taisei Kayaki, Kinuko Nishikawa, Mitsujiro Osawa, Akira Niwa, Toshiki Takenouchi, et al. Involvement of mTOR pathway in neurodegeneration in NSF-related developmental and epileptic encephalopathy. Human molecular genetics. 2023. 32. 10. 1683-1697
  • Shigeharu Oh, Akira Niwa, Ayako Nagahashi, Isao Asaka, Tatsutoshi Nakahata, Megumu K Saito. iPS cells from Chediak-Higashi syndrome patients recapitulate the giant granules in myeloid cells. Pediatrics international : official journal of the Japan Pediatric Society. 2022. 64. 1. e15390
もっと見る
MISC (79件):
講演・口頭発表等 (13件):
  • NK Cells from Human Pluripotent Stem Cells for Immunotherapy
    (BLOOD 2018)
  • iPSC-Based Phenomic Screen Revealed an Impact of Uncontrolled NFkB Activity at the Initiating Stages of AML1-ETO Related Leukemia
    (BLOOD 2018)
  • Identification of Candidate Progenitor Populations Which Causes Transient Abnormal Myelopoiesis
    (BLOOD 2017)
  • Exogenously Added Cofilin Increases Ex Vivo Production of Functional Platelets By Stimulating Proplatelet Formation
    (BLOOD 2017)
  • PSC-Derived Hematopoietic System to Elucidate the Cooperation Between Gene Alterations and Cell Lineages in Leukemogenesis
    (BLOOD 2016)
もっと見る
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