小林稔

Kobayashi Minoru

所属機関・部署：

研究分野 (1件)：細胞生物学

競争的資金等の研究課題 (12件)：

全件表示

論文 (30件)：

Yukari SHIRAI, Tatsuya SUWA, Minoru KOBAYASHI, Sho KOYASU, Hiroshi HARADA. DDX5 enhances HIF-1 activity by promoting the interaction of HIF-1α with HIF-1β and recruiting the resulting heterodimer to its target gene loci. Biology of the Cell. 2023
Sho Koyasu, Shoichiro Horita, Keisuke Saito, Minoru Kobayashi, Hiroshi Ishikita, Christalle Ct Chow, Gouki Kambe, Shigeto Nishikawa, Toshi Menju, Akiyo Morinibu, et al. ZBTB2 links p53 deficiency to HIF-1-mediated hypoxia signaling to promote cancer aggressiveness. EMBO reports. 2022. e202154042
Takao Haitani, Minoru Kobayashi, Sho Koyasu, Shusuke Akamatsu, Tatsuya Suwa, Yasuhito Onodera, Jin-Min Nam, Phuong Thi Lien Nguyen, Toshi Menju, Hiroshi Date, et al. Proteolysis of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase. Cancer letters. 2022. 528. 76-84
Tatsuya Suwa, Minoru Kobayashi, Yukari Shirai, Jin-Min Nam, Yoshiaki Tabuchi, Norihiko Takeda, Shusuke Akamatsu, Osamu Ogawa, Takashi Mizowaki, Ester M Hammond, et al. SPINK1 as a plasma marker for tumor hypoxia and a therapeutic target for radiosensitization. JCI insight. 2021. 6. 21
Tatsuya Suwa, Minoru Kobayashi, Jin-Min Nam, Hiroshi Harada. Tumor microenvironment and radioresistance. Experimental & Molecular Medicine. 2021

MISC (8件)：

小林稔, 平岡, 真寛, 原田浩. 時計遺伝子PER2と低酸素応答機構の相互作用メカニズムの解析. 2014
小林稔, 曽麗華, 後藤容子, 井上実, 板坂聡, 吉村通央, 原田浩, 平岡真寛. IDH3はHIF-1alphaを安定化して腫瘍増殖を亢進する. 2013
小林稔, 脇田大功, 岩淵禎弘, 佐藤崇之, 北村, 秀光, 西村孝司. Method for establishment of cancer stem-like cells by introduction of oncogenes into mesenchymal stem cells. 2013
Establishment of airway smooth muscle cell line useful for evaluating neuro-immuno cross-talk in Th1-mediated airway inflammation. 2011
The pivotal role of IFN-gamma in Th1- and Th17-mediated steroid-resistant airway hyperresponsiveness. 2010

講演・口頭発表等 (22件)：

Decreased expression levels of a histone acetyl reader, ATAD2, induces chemoresistance of cancer cells under severe hypoxia by inhibiting cell cycle progression in S phase
(第18回がんとハイポキシア研究会 2022)
DNA double strand breaksのインビボ定量評価に向けたEGFP-53BP1ノックインマウスの樹立
(第62回日本放射線影響学会 2019)
A Circadian Clock Gene, PER2, Activates HIF-1 as an Effector Molecule for Recruitment of HIF-1α to Promoter Regions of Its Downstream Genes
(第34回放生研国際シンポジウム 2018)
HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating Shh.
(第77回日本癌学会学術総会 2018)
A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of Its downstream genes
(The 17th International Joint Mini-Symposium on Molecular and Cell Biology 2018)

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小林 稔