文献

J-GLOBAL ID：201502276998380990   整理番号：15A0590007

同所性腫瘍異種移植片モデルのリポソーム取り込みと微小血管分布における不均一性の空間的と時間的マッピング

Spatial and temporal mapping of heterogeneity in liposome uptake and microvascular distribution in an orthotopic tumor xenograft model

著者 (14件)： EKDAWI Sandra N. (Leslie Dan Fac. of Pharmacy, Univ. of Toronto, Toronto, Ontario M5S 3M2, CAN) ,  STEWART James M.P. (Inst. of Biomaterials and Biomedical Engineering, Univ. of Toronto, Toronto, Ontario M5S 3G9, CAN) ,  DUNNE Michael (Leslie Dan Fac. of Pharmacy, Univ. of Toronto, Toronto, Ontario M5S 3M2, CAN) ,  STAPLETON Shawn (Dep. of Medical Biophysics, Univ. of Toronto, Toronto, Ontario M5G 1L7, CAN) ,  STAPLETON Shawn (Radiation Medicine Program, Princess Margaret Cancer Centre, Univ. Health Network, Toronto, Ontario M5G 2M9, CAN) ,  MITSAKAKIS Nicholas (Leslie Dan Fac. of Pharmacy, Univ. of Toronto, Toronto, Ontario M5S 3M2, CAN) ,  DOU Yannan N. (Leslie Dan Fac. of Pharmacy, Univ. of Toronto, Toronto, Ontario M5S 3M2, CAN) ,  JAFFRAY David A. (Inst. of Biomaterials and Biomedical Engineering, Univ. of Toronto, Toronto, Ontario M5S 3G9, CAN) ,  JAFFRAY David A. (Dep. of Medical Biophysics, Univ. of Toronto, Toronto, Ontario M5G 1L7, CAN) ,  JAFFRAY David A. (Dep. of Radiation Oncology, Univ. of Toronto, Toronto, Ontario M5S 3E2, CAN) ,  JAFFRAY David A. (Radiation Medicine Program, Princess Margaret Cancer Centre, Univ. Health Network, Toronto, Ontario M5G 2M9, CAN) ,  JAFFRAY David A. (Ontario Cancer Inst., Toronto, Ontario M5G 2M9, CAN) ,  JAFFRAY David A. (Techna Inst., Univ. Health Network, Toronto, Ontario M5G 1P5, CAN) ,  ALLEN Christine (Leslie Dan Fac. of Pharmacy, Univ. of Toronto, Toronto, Ontario M5S 3M2, CAN)
資料名： Journal of Controlled Release  (Journal of Controlled Release)
巻： 207  ページ： 101-111  発行年： 2015年06月10日 
JST資料番号： C0308D  ISSN： 0168-3659  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： ナノに基づく薬剤デリバリーでの既存のパラダイムは,現在,困難...

シソーラス用語： 移植片 ,...
準シソーラス用語： 腫瘍異種移植片 ,...

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分類 (4件)： 腫ようの化学・生化学・病理学  (GE02030N) ,  細胞生理一般  (EF02010S) ,  基礎治療学  (GC03012A) ,  基礎診断学  (GC03002P)

引用文献 (72件)：

• A.J. Primeau, A. Rendon, D. Hedley, L Lilge, I.F. Tannock, The distribution of the anticancer drug doxorubicin in relation to blood vessels in solid tumors, Clin. Cancer Res. 11 (2005) 8782-8788.
• KJ. Patel, I.F. Tannock, The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors, BMC Cancer 9 (2009) 356.
• R.H. Grantab, I.F. Tannock, Penetration of anticancer drugs through tumour tissue as a function of cellular packing density and interstitial fluid pressure and its modification by bortezomib, BMC Cancer 12 (2012) 214.
• K.J. Patel, O. Tredan, I.F. Tannock, Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues, Cancer Chemother. Pharmacol. 72 (2013) 127-138.
• KJ. Patel, C. Lee, Q, Tan, I.F. Tannock, Use of the proton pump inhibitor pantoprazole to modify the distribution and activity of doxorubicin: a potential strategy to improve the therapy of solid tumors, Clin. Cancer Res. 19 (2013) 6766-6776.

タイトルに関連する用語 (9件)： 同所性 ,  腫瘍異種移植片 ,  モデル ,  リポソーム ,  取り込み ,  微小 ,  血管分布 ,  不均一性 ,  マッピング