文献

J-GLOBAL ID：201602244508005631   整理番号：16A1001613

多分子型SOD抱合体のサイズおよびPECAMとICAM標的化はその抱合体の内皮輸送,内部移行と防御効果を制御する

Size and targeting to PECAM vs ICAM control endothelial delivery, internalization and protective effect of multimolecular SOD conjugates

著者 (7件)： Shuvaev Vladimir V. (Department of Systems Pharmacology and Translational Therapeutics, Center for Translational Targeted Therapeutics and Nanomedicine of the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA) ,  Muro Silvia (Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA) ,  Arguiri Evguenia (Department of Medicine, Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA) ,  Khoshnejad Makan (Department of Systems Pharmacology and Translational Therapeutics, Center for Translational Targeted Therapeutics and Nanomedicine of the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA) ,  Tliba Samira (Department of Systems Pharmacology and Translational Therapeutics, Center for Translational Targeted Therapeutics and Nanomedicine of the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA) ,  Christofidou-Solomidou Melpo (Department of Medicine, Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA) ,  Muzykantov Vladimir R. (Department of Systems Pharmacology and Translational Therapeutics, Center for Translational Targeted Therapeutics and Nanomedicine of the Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA)
資料名： Journal of Controlled Release  (Journal of Controlled Release)
巻： 234  ページ： 115-123  発行年： 2016年07月28日 
JST資料番号： C0308D  ISSN： 0168-3659  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： SODの内皮制御輸送は虚血再灌流,炎症および他の疾患状態が関...

シソーラス用語： *スーパーオキシドジスムターゼ ,...
準シソーラス用語： PECAM ,...

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著者キーワード (5件)： Intracellular delivery ,  Endothelial cells ,  Vascular immunotargeting ,  Cell adhesion molecules ,  Endocytosis

分類 (3件)： 生物薬剤学(基礎)  (GY01021U) ,  酵素一般  (EB09010D) ,  免疫反応一般  (ED03010T)

引用文献 (29件)：

• W.A. den Hengst, J.F. Gielis, J.Y. Lin, P.E. Van Schil, L.J. De Windt, A.L. Moens, Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process, Am. J. Physiol. Heart Circ. Physiol. 299 (5) (2010) H1283-H1299.
• S.R. Thomas, P.K. Witting, G.R. Drummond, Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities, Antioxid. Redox Signal. 10 (10) (2008) 1713-1765.
• V. Bagalkot, M.A. Badgeley, T. Kampfrath, J.A. Deiuliis, S. Rajagopalan, A. Maiseyeu, Hybrid nanoparticles improve targeting to inflammatory macrophages through phagocytic signals, J. Control. Release 217 (2015) 243-255.
• X. Yun, V.D. Maximov, J. Yu, H. Zhu, A.A. Vertegel, M.S. Kindy, Nanoparticles for targeted delivery of antioxidant enzymes to the brain after cerebral ischemia and reperfusion injury, J. Cereb. Blood Flow Metab. 33 (4) (2013) 583-592.
• P.S. Kowalski, P.R. Kuninty, K.T. Bijlsma, M.C. Stuart, N.G. Leus, M.H. Ruiters, G. Molema, J.A. Kamps, SAINT-liposome-polycation particles, a new carrier for improved delivery of siRNAs to inflamed endothelial cells, Eur. J. Pharm. Biopharm. 89 (2015) 40-47.

タイトルに関連する用語 (11件)： 分子 ,  SOD ,  抱合体 ,  サイズ ,  PECAM ,  ICAM ,  標的化 ,  内皮 ,  輸送 ,  移行 ,  防御効果