文献

J-GLOBAL ID：201602271781773837   整理番号：16A0776083

Alzheimer病の神経炎症のin vivoイメージング

In vivo imaging of neuroinflammation in Alzheimer’s disease

著者 (5件)： Higuchi Makoto (National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan) ,  Ji Bin (National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan) ,  Maeda Jun (National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan) ,  Sahara Naruhiko (National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan) ,  Suhara Tetsuya (National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan)
資料名： Clinical and Experimental Neuroimmunology (Web)  (Clinical and Experimental Neuroimmunology (Web))
巻： 7  号： 2  ページ： 139-144  発行年： 2016年 
JST資料番号： U0510A  ISSN： 1759-1961  資料種別： 逐次刊行物 (A)
記事区分： 解説  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 多様な神経系認知症はAlzheimer病でβアミロイドペプチ...

シソーラス用語： *Alzheimer病 ,...
準シソーラス用語： 免疫反応 ,...

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著者キーワード (3件)： positron emission tomography ,  purinergic receptor ,  translocator protein

分類 (1件)： 神経の基礎医学  (GN01020W)

引用文献 (25件)：

• Higuchi M, Maeda J, Ji B, et al. In-vivo visualization of key molecular processes involved in Alzheimer’s disease pathogenesis: insights from neuroimaging research in humans and rodent models. Biochim Biophys Acta. 2010; 1802: 373-88.
• Maeda J, Zhang MR, Okauchi T, et al. In vivo positron emission tomographic imaging of glial responses to amyloid-β and tau pathologies in mouse models of Alzheimer’s disease and related disorders. J Neurosci . 2011; 31: 4720-30.
• Yasuno F, Ota M, Kosaka J, et al. Increased binding of peripheral benzodiazepine receptor in Alzheimer’s disease measured by positron emission tomography using [¹¹C]DAA1106. Biol Psychiatry. 2008; 64: 835-41.
• Ji B, Maeda J, Sawada M, et al. Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer’s disease and other CNS pathologies. J Neurosci. 2008; 28: 12255-67.
• Yoshiyama Y, Higuchi M, Zhang B, et al. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron. 2007; 53: 337-51.

タイトルに関連する用語 (3件)： Alzheimer病 ,  神経炎症 ,  イメージング