文献

J-GLOBAL ID：201602293821614631   整理番号：16A1176016

歯髄幹細胞の移植は抗炎症表現型へのマクロファージの分化を促進し,糖尿病性多発神経障害を改善することによって坐骨神経における炎症を抑制した

Transplantation of dental pulp stem cells suppressed inflammation in sciatic nerves by promoting macrophage polarization towards anti-inflammation phenotypes and ameliorated diabetic polyneuropathy

著者 (12件)： Omi Maiko (Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Hata Masaki (Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Nakamura Nobuhisa (Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Miyabe Megumi (Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Kobayashi Yasuko (Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Kamiya Hideki (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Nakamura Jiro (Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Japan) ,  Ozawa Shogo (Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Tanaka Yoshinobu (Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Takebe Jun (Department of Removable Prosthodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Matsubara Tatsuaki (Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, Japan) ,  Naruse Keiko (Department of Internal Medicine, School of Dentistry, Aichi Gakuin University, Nagoya, Japan)
資料名： Journal of Diabetes Investigation (Web)  (Journal of Diabetes Investigation (Web))
巻： 7  号： 4  ページ： 485-496  発行年： 2016年 
JST資料番号： U0507A  ISSN： 2040-1124  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： 目的/導入:歯髄幹細胞(DPSC)は,細胞治療にとって魅力的...

シソーラス用語： ラット ,...
準シソーラス用語： *糖尿病性多発神経障害

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著者キーワード (3件)： Cell transplantation ,  Dental pulp stem cells ,  Diabetic polyneuropathy

分類 (3件)： 代謝異常・栄養性疾患一般  (GD05010J) ,  神経の基礎医学  (GN01020W) ,  生体防御と免疫系一般  (ED01010F)

引用文献 (42件)：

• Tesfaye S. Recent advances in the management of diabetic symmetrical polyneuropathy. J Diabetes Investig 2010; 2: 33-42.
• Naruse K, Hamada Y, Nakashima E, et al. Therapeutic neovascularization using cord blood-derived endothelial progenitor cells for diabetic neuropathy. Diabetes 2005; 54: 1823-1828.
• Naruse K, Sato J, Funakubo M, et al. Transplantation of bone marrow-derived mononuclear cells improves mechanical hyperalgesia, cold allodynia and nerve function in diabetic neuropathy. PLoS One 2011; 6: e27458.
• Shibata T, Naruse K, Kamiya H, et al. Transplantation of bone marrow-derived mesenchymal stem cells improves diabetic polyneuropathy in rats. Diabetes 2008; 57: 3099-3107.
• Himeno T, Kamiya H, Naruse K, et al. Angioblast derived from ES cells construct blood vessels and ameliorate diabetic polyneuropathy in mice. J Diabetes Res 2015; 2015: 257230.

タイトルに関連する用語 (9件)： 歯髄幹細胞 ,  移植 ,  炎症 ,  表現型 ,  マクロファージ ,  分化 ,  促進 ,  糖尿病性多発神経障害 ,  坐骨神経