文献

J-GLOBAL ID：201702222619644824   整理番号：17A0972350

B-cell lymphoma 6の過剰発現は骨髄腫細胞株における遺伝子発現プロファイルを変化させ,DNA損傷応答の低下と関連する

Overexpression of B-cell lymphoma 6 alters gene expression profile in a myeloma cell line and is associated with decreased DNA damage response

著者 (13件)： Tahara Kenichi (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Takizawa Makiko (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Yamane Arito (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Osaki Yohei (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Ishizaki Takuma (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Mitsui Takeki (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Yokohama Akihiko (Division of Blood Transfusion Service, Gunma University Hospital, Gunma, Japan) ,  Saitoh Takayuki (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Gunma, Japan) ,  Tsukamoto Norifumi (Oncology Center, Gunma University Hospital, Gunma, Japan) ,  Matsumoto Morio (Department of Hematology, National Hospital Organization Nishigunma National Hospital, Gunma, Japan) ,  Murakami Hirokazu (Department of Laboratory Sciences, Gunma University Graduate School of Health Sciences, Gunma, Japan) ,  Nojima Yoshihisa (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan) ,  Handa Hiroshi (Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 108  号： 8  ページ： 1556-1564  発行年： 2017年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： B-cell lymphoma 6(BCL6)は,遺伝子抑制...

シソーラス用語： *癌遺伝子 ,...
準シソーラス用語： AID【酵素】 ,...

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著者キーワード (5件)： ATM ,  BCL6 ,  DNA repair ,  IL-6 ,  multiple myeloma

分類 (2件)： 基礎腫よう学一般  (GE02010R) ,  血液の腫よう  (GK04000M)

引用文献 (45件)：

• Kuehl WM, Bergsagel PL. Multiple myeloma: evolving genetic events and host interactions. Nat Rev Cancer 2002; 2: 175-87.
• Neri P, Bahlis NJ. Genomic instability in multiple myeloma: mechanisms and therapeutic implications. Expert Opin Biol Ther 2013; 13(Suppl 1): S69-82.
• Shammas MA, Shmookler Reis RJ, Koley H, Batchu RB, Li C, Munshi NC. Dysfunctional homologous recombination mediates genomic instability and progression in myeloma. Blood 2009; 113: 2290-7.
• Herrero AB, San Miguel J, Gutierrez NC. Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability. PLoS ONE 2015; 10: e0121581.
• Koduru S, Wong E, Strowig T et al. Dendritic cell-mediated activation-induced cytidine deaminase (AID)-dependent induction of genomic instability in human myeloma. Blood 2012; 119: 2302-9.

タイトルに関連する用語 (5件)： 過剰発現 ,  骨髄腫 ,  細胞株 ,  遺伝子発現プロファイル ,  DNA損傷応答