文献

J-GLOBAL ID：201702222646432396   整理番号：17A1764050

デコイ受容体3の遺伝子学的および薬理学的補充による非アルコール性脂肪性肝炎の進行および発症を予防および阻害するメカニズム

Mechanisms of the prevention and inhibition of the progression and development of non-alcoholic steatohepatitis by genetic and pharmacological decoy receptor 3 supplementation

著者 (26件)： Lee Pei-Chang (Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan) ,  Lee Pei-Chang (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Lee Pei-Chang (Division of Gastroenterology and Hepatology, Department of Medicine, Yuanshan Branch, Taipei Veterans General Hospital, Yilan, Taiwan) ,  Yang Ling-Yu (Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Wang Ying-Wen (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Wang Ying-Wen (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Huang Shiang-Fen (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Huang Shiang-Fen (Division of Infection, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lee Kuei-Chuan (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Lee Kuei-Chuan (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Hsieh Yun-Cheng (Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan) ,  Hsieh Yun-Cheng (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Hsieh Yun-Cheng (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Yang Ying-Ying (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Yang Ying-Ying (Department of Medical Education, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Yang Ying-Ying (Division of General Medicine, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Yang Ying-Ying (Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Hsieh Shie-Liang (Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Hsieh Shie-Liang (Genomics Research Center, Academia Sinica, Taipei, Taiwan) ,  Hou Ming-Chih (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Hou Ming-Chih (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lin Han-Chieh (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Lin Han-Chieh (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lee Fa-Yuah (Faculty of Medicine, National Yang-Ming University, Taipei, Taiwan) ,  Lee Fa-Yuah (Division of Gastroenterology and Hepatology, Taipei Veterans General Hospital, Taipei, Taiwan) ,  Lee Shou-Dong (Cheng Hsin General Hospital, Taipei, Taiwan)
資料名： Hepatology Research  (Hepatology Research)
巻： 47  号： 12  ページ： 1260-1271  発行年： 2017年11月 
JST資料番号： W1284A  ISSN： 1386-6346  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オーストラリア (AUS)  言語： 英語 (EN)

抄録/ポイント： 目的:非アルコール性脂肪性肝炎(NASH)の治療は,治療法が...

シソーラス用語： 薬物 ,...
準シソーラス用語： DcR3 ,...

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著者キーワード (3件)： デコイ受容体3 ,  M1分極 ,  非アルコール性脂肪性肝炎

分類 (1件)： 消化器の基礎医学  (GH01020E)

引用文献 (46件)：

• Reid AE. Nonalcoholic steatohepatitis. Gastroenterology 2001; 121: 710-23.
• Chatterjee S, Ganini D, Tokar EJ et al. Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis. J Hepatol 2013; 58: 778-84.
• Li Z, Soloski MJ, Diehl AM. Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease. Hepatology 2005; 42: 880-5.
• Seth RK, Das S, Pourhoseini S et al. M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. J Pharmacol Exp Ther 2015; 352: 77-89.
• Maina V, Sutti S, Locatelli I et al. Bias in macrophage activation pattern influences non-alcoholic steatohepatitis (NASH) in mice. Clin Sci (Lond) 2012; 122: 545-53.

タイトルに関連する用語 (10件)： デコイ ,  受容体 ,  遺伝子学 ,  薬理学 ,  補充 ,  非アルコール性脂肪性肝炎 ,  発症 ,  予防 ,  阻害 ,  メカニズム