文献

J-GLOBAL ID：201702237109844175   整理番号：17A1812378

OLETFラットの大腿動脈でのスーパーオキシド産生におけるグリセルアルデヒド由来AGEとミトコンドリアの役割とプラバスタチンの作用

Role of Glyceraldehyde-Derived AGEs and Mitochondria in Superoxide Production in Femoral Artery of OLETF Rat and Effects of Pravastatin

著者 (9件)： Hori Eisei (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University) ,  Kikuchi Chigusa (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University) ,  Kikuchi Chigusa (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University) ,  Nagami Chie (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University) ,  Kajikuri Junko (Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University) ,  Itoh Takeo (Department of Pharmacology, Graduate School of Medical Sciences, Nagoya City University) ,  Takeuchi Masayoshi (Department of Advanced Medicine, Medical Research Institute, Kanazawa Medical University) ,  Matsunaga Tamihide (Department of Clinical Pharmacy, Graduate School of Pharmaceutical Sciences, Nagoya City University) ,  Matsunaga Tamihide (Educational Research Center for Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Nagoya City University)
資料名： Biological and Pharmaceutical Bulletin  (Biological and Pharmaceutical Bulletin)
巻： 40  号： 11  ページ： 1903-1908(J-STAGE)  発行年： 2017年 
JST資料番号： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 糖尿病の合併症には血管スーパーオキシドの過剰産生があり,これ...

シソーラス用語： ラット ,...
準シソーラス用語： OLETFラット ,...

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著者キーワード (12件)： type 2 diabetes ,  superoxide ,  mitochondria ,  advanced glycation end-product ,  Otsuka Long-Evans Tokushima Fatty rat ,  pravastatin ,  type 2 diabetes ,  superoxide ,  mitochondria ,  advanced glycation end-product ,  Otsuka Long-Evans Tokushima Fatty rat ,  pravastatin

分類 (1件)： 循環系の基礎医学  (GJ01020K)

物質索引 (1件)： プラバスタチン

引用文献 (29件)：

• 1) Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, Bell K, Caporusso J, Durand-Zaleski I, Komori K, Lammer J, Liapis C, Novo S, Razavi M, Robbs J, Schaper N, Shigematsu H, Sapoval M, White C, White J, Clement D, Creager M, Jaff M, Mohler E 3rd, Rutherford RB, Sheehan P, Sillesen H, Rosenfield K, TASC II Working Group. Inter-society consensus for the management of peripheral arterial disease (TASC II). J. Vasc. Surg., 45, S5-S67 (2007).
• 2) Fatehi-Hassanabad Z, Chan CB, Furman BL. Reactive oxygen species and endothelial function in diabetes. Eur. J. Pharmacol., 636, 8-17 (2010).
• 3) Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature, 404, 787-790 (2000).
• 4) Matsui T, Nishino Y, Takeuchi M, Yamagishi S. Vildagliptin blocks vascular injury in thoracic aorta of diabetic rats by suppressing advanced glycation end product-receptor axis. Pharmacol. Res., 63, 383-388 (2011).
• 5) Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes, 49, 1939-1945 (2000).

タイトルに関連する用語 (7件)： OLETFラット ,  大腿動脈 ,  スーパーオキシド ,  グリセルアルデヒド ,  ミトコンドリア ,  役割 ,  プラバスタチン