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J-GLOBAL ID：201702242491975475   整理番号：17A1390140

急性呼吸窮迫症候群患者における疫学,治療のパターンおよび転帰の地質経済学的変化:肺安全前向きコホート研究からの洞察【Powered by NICT】

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study

著者 (55件)： Laffey John G (Department of Anesthesia, St Michael’s Hospital, Toronto, ON, Canada) ,  Laffey John G (Department of Critical Care Medicine, St Michael’s Hospital, Toronto, ON, Canada) ,  Laffey John G (Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada) ,  Laffey John G (Department of Anesthesia, University of Toronto, Toronto, ON, Canada) ,  Laffey John G (Department of Physiology, University of Toronto, Toronto, ON, Canada) ,  Laffey John G (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Madotto Fabiana (Research Center on Public Health, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy) ,  Bellani Giacomo (Research Center on Public Health, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy) ,  Bellani Giacomo (Department of Emergency and Intensive Care, San Gerardo Hospital, Monza, Italy) ,  Pham Tai (Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada) ,  Pham Tai (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Pham Tai (Sorbonne Universites, UPMC Universite Paris 06, Paris, France) ,  Fan Eddy (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Fan Eddy (Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada) ,  Fan Eddy (Department of Medicine, University Health Network and Mount Sinai Hospital, Toronto, ON, Canada) ,  Brochard Laurent (Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada) ,  Brochard Laurent (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Amin Pravin (Department of Critical Care Medicine, Bombay Hospital Institute of Medical Sciences, Mumbai, India) ,  Arabi Yaseen (Intensive Care Department, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia) ,  Arabi Yaseen (Respiratory Services, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia) ,  Arabi Yaseen (King Abdullah International Medical Research Center, Riyadh, Saudi Arabia) ,  Bajwa Ednan K (Division of Pulmonary and Critical Care, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA) ,  Bruhn Alejandro (Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile) ,  Cerny Vladimir (Department of Anesthesiology, Perioperative Medicine and Intensive Care, J E Purkinje University, Masaryk Hospital, Usti nad Labem, Czech Republic) ,  Cerny Vladimir (Department of Research and Development, and Department of Anesthesiology and Intensive Care, Charles University in Prague, Prague, Czech Republic) ,  Cerny Vladimir (Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic) ,  Clarkson Kevin (Department of Anaesthesia, Galway University Hospitals and National University of Ireland, Galway, Galway, Ireland) ,  Heunks Leo (Department of Intensive Care, VU University Medical Centre Amsterdam, Netherlands) ,  Kurahashi Kiyoyasu (Department of Anesthesiology and Intensive Care Medicine, School of Medicine, International University of Health and Welfare, Narita, Japan) ,  Laake Jon Henrik (Division of Critical Care, Department of Anaesthesiology, Rikshospitalet Medical Centre, Oslo University Hospital, Oslo, Norway) ,  Lorente Jose A (CIBER de Enfermedades Respiratorias, Hospital Universitario de Getafe, Universidad Europea, Madrid, Spain) ,  McNamee Lia (Centre for Experimental Medicine, Queen’s University of Belfast, Belfast, Northern Ireland, UK) ,  McNamee Lia (Wellcome-Wolfson Institute for Experimental Medicine, Belfast, Northern Ireland, UK) ,  McNamee Lia (Regional Intensive Care Unit, Royal Victoria Hospital A&E, Grosvenor Road, Belfast, Northern Ireland, UK) ,  Nin Nicolas (CIBER de Enfermedades Respiratorias, Hospital Universitario de Getafe, Universidad Europea, Madrid, Spain) ,  Nin Nicolas (Hospital Espanol, Montevideo, Uruguay) ,  Palo Jose Emmanuel (Section of Adult Critical Care, Department of Medicine, The Medical City, Pasig, Philippines) ,  Piquilloud Lise (Adult Intensive Care and Burn Unit, University Hospital of Lausanne, Lausanne, Switzerland) ,  Piquilloud Lise (Department of Medical Intensive Care, University Hospital of Angers, Angers, France) ,  Qiu Haibo (Department of Critical Care Medicine, Nanjing Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China) ,  Jimenez Juan Ignacio Silesky (Department of Intensive Care, Hospital San Juan de Dios, and Department of Intensive Care, Hospital CIMA San Jose, Council of Critical Medicine, University of Costa Rica, San Pedro Montes de Oca, Costa Rica) ,  Esteban Andres (CIBER de Enfermedades Respiratorias, Hospital Universitario de Getafe, Universidad Europea, Madrid, Spain) ,  Esteban Andres (Hospital Espanol, Montevideo, Uruguay) ,  McAuley Daniel F (Centre for Experimental Medicine, Queen’s University of Belfast, Belfast, Northern Ireland, UK) ,  McAuley Daniel F (Wellcome-Wolfson Institute for Experimental Medicine, Belfast, Northern Ireland, UK) ,  McAuley Daniel F (Regional Intensive Care Unit, Royal Victoria Hospital A&E, Grosvenor Road, Belfast, Northern Ireland, UK) ,  van Haren Frank (Intensive Care Unit, Canberra Hospital, Canberra, ACT, Australia) ,  van Haren Frank (Australian National University, Canberra, ACT, Australia) ,  Ranieri Marco (Sapienza Universita di Roma, Dipartimento di Anestesia e Rianimazione, Policlinico Umberto I, Rome, Italy) ,  Rubenfeld Gordon (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Rubenfeld Gordon (Program in Trauma, Emergency and Critical Care, Sunnybrook Health Sciences Center, Toronto, ON, Canada) ,  Wrigge Hermann (Department of Anesthesiology and Intensive Care Medicine, University of Leipzig, Leipzig, Germany) ,  Slutsky Arthur S (Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael’s Hospital, Toronto, ON, Canada) ,  Slutsky Arthur S (Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada) ,  Pesenti Antonio (Dipartimento di Anestesia, Rianimazione ed Emergenza Urgenza, Fondazione IRCCS Ca Granda-Ospedale Maggiore Policlinico and Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Universita degli Studi di Milano, Milan, Italy)
資料名： Lancet Respiratory Medicine  (Lancet Respiratory Medicine)
巻： 5  号： 8  ページ： 627-638  発行年： 2017年 
JST資料番号： W3111A  ISSN： 2213-2600  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 人口統計学,管理,および転帰急性呼吸窮迫症候群(ARDS)患者の地理経済変動に関する利用可能な情報はほとんどない。重症急性呼吸不全(LUNG SAFE)の世界的影響を理解するための大規模観察研究に登録された患者におけるこれらの地理経済変動の影響を特性化することを目的とした。肺安全は六大陸にわたる50カ国,459の集中治療室の便宜的標本における,2014,冬に4週間の間に実施された。組み入れ基準は,侵襲性または非侵襲的換気の登録窓とレセプト内参加集中治療室(移動を含む)に入院した。試験の二次目的の一つは,人口統計,管理,ARDS患者の転帰の変化を特性化することであった。2016世界銀行国分類を用いて三の主要な地理経済グループ,すなわちヨーロッパ高所得国(ヨーロッパ高),世界の残りの部分で高所得国(rWORLD高),および中所得国(中部)を定義した。はこれらの三群の患者の転帰を比較した。肺安全はClinicalTrials.gov,数NCT02010073と関係づけた。1日目または2日目にARDS基準を満たした肺安全に登録された2813名の患者のうち,1521(54%)は中期国からヨーロッパ高,rWORLD高から746(27%),および546(19%)から募集した。人口統計の顕著な地理的変動,ARDSに対する危険因子および併存疾患を認めた。重度急性呼吸窮迫症候群または動脈血酸素(PaO_2)の分圧吸気(F_O_2)150以下で酸素濃度への比を持つ患者の割合は,二種の他の地域よりもrWORLD高国で有意に低かった。腹臥位と神経筋遮断の使用は他の二地域よりもヨーロッパ高国に有意に多くみられた。集中治療室での侵襲的人工呼吸と長さの調整期間はヨーロッパ高ないし中期の国よりrWORLD高国の患者で有意に短かった。ARDSにおける生存率増加と関連していた一人当たりの総国民所得院内生存率はヨーロッパ高またはrWORLD高の国より中期国で有意に低かった。重症度,臨床医認識,ARDSの管理,患者の転帰に存在する重要な地理経済差異。ARDSにおける人と転帰当たり所得は独立して関連していた。ヨーロッパ集中治療医学会,St MichaelのMilan-Bicoccaの病院,大学。Copyright 2017 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： *疫学 ,  キャラクタリゼーション ,  *安全性 ,  危険因子 ,  病院 ,  *前向きコホート研究 ,  *患者 ,  人工呼吸 ,  ヨーロッパ ,  ICU【医療】 ,  *経済学 ,  生存率 ,  地理学
準シソーラス用語： 患者予後 ,  *転帰 , 【Automatic Indexing@JST】

分類 (2件)： 医療用機器装置  (GA05020L) ,  呼吸器疾患の治療一般  (GI05010Y)

タイトルに関連する用語 (10件)： 急性呼吸窮迫症候群 ,  患者 ,  疫学 ,  治療 ,  転帰 ,  地質 ,  経済 ,  肺 ,  前向きコホート研究 ,  洞察