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J-GLOBAL ID：201702251424680391   整理番号：17A0793913

増幅標的シグナルと強化抗癌効果のための中継ドラッグデリバリー【Powered by NICT】

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy

著者 (14件)： Hu Quanyin (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Hu Quanyin (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Sun Wujin (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Sun Wujin (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Qian Chenggen (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Qian Chenggen (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Qian Chenggen (Department of Polymer Science and Engineering and Key Laboratory of High Performance Polymer Materials and Technology of MOE, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, China) ,  Bomba Hunter N. (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Bomba Hunter N. (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Xin Hongliang (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Xin Hongliang (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Gu Zhen (Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA) ,  Gu Zhen (Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA) ,  Gu Zhen (Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA)
資料名： Advanced Materials  (Advanced Materials)
巻： 29  号： 13  ページ： ROMBUNNO.201605803  発行年： 2017年 
JST資料番号： W0001A  ISSN： 0935-9648  CODEN： ADVMEW  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： ドイツ (DEU)  言語： 英語 (EN)

抄録/ポイント： NC_Aにより生成された放送信号を受信して腫瘍部位で蓄積できることを腫瘍血管炎症を特異的に誘導することをシグナル伝達ナノキャリアA(NC_A)発生と実行生体模倣ナノキャリアB(NC_B)から構成される,二つの異なるモジュールに基づく「リレードラッグデリバリー」システムは,活性腫瘍標的化信号を増幅し,抗腫瘍治療を向上させるために開発した。Copyright 2017 Wiley Publishing Japan K.K. All Rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： *抗腫瘍作用 ,  炎症 ,  *ドラッグデリバリーシステム ,  ターゲティング
準シソーラス用語： 生体模倣 ,  腫瘍治療 ,  腫瘍標的 ,  ナノキャリア ,  腫瘍血管 , 【Automatic Indexing@JST】

著者キーワード (5件)： 活性標的化 ,  増幅 ,  生体模倣 ,  ドラッグデリバリー ,  炎症

分類 (4件)： 顕微鏡法  (BK01040E) ,  界面化学一般  (CB12010J) ,  固-気界面一般  (CB12041H) ,  固体の表面構造一般  (BK15010E)

タイトルに関連する用語 (7件)： 増幅 ,  標的 ,  シグナル ,  強化 ,  抗癌効果 ,  中継 ,  ドラッグデリバリー