文献

J-GLOBAL ID：201702258980615948   整理番号：17A1697903

ソラソジンはAKT/グリコーゲンシンターゼキナーゼ-3β/β-カテニン経路の抑制を介してヒト結腸直腸癌細胞を阻害する

Solasodine inhibits human colorectal cancer cells through suppression of the AKT/glycogen synthase kinase-3β/β-catenin pathway

著者 (22件)： Zhuang Yu-wen (Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China) ,  Zhuang Yu-wen (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Zhuang Yu-wen (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Wu Cun-en (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Wu Cun-en (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Zhou Jin-yong (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Zhou Jin-yong (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Chen Xu (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Chen Xu (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Wu Jian (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Wu Jian (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Jiang Shan (Division of Membrane Dynamics, Department of Physiology and Cell Biology, Kobe University Graduate School of Medicine, Kobe, Japan) ,  Peng Hai-yan (The First Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China) ,  Peng Hai-yan (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Zou Xi (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Liu Jia-yun (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Wu Da-peng (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Gong Tao (Nanjing Hospital of Traditional Chinese Medicine, Nanjing, China) ,  Qi Ming-hao (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Xue Tian (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Liu Shen-lin (Jiangsu Province Hospital of TCM, The Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, china) ,  Cai Hui (Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China)
資料名： Cancer Science (Web)  (Cancer Science (Web))
巻： 108  号： 11  ページ： 2248-2264  発行年： 2017年 
JST資料番号： U0505A  ISSN： 1349-7006  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： アメリカ合衆国 (USA)  言語： 英語 (EN)

抄録/ポイント： ソラソジンは抗酸化と抗感染と神経形成促進を含む広範囲の機能を...

シソーラス用語： *腫瘍細胞 ,...
準シソーラス用語： *結腸直腸癌細胞 ,...

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著者キーワード (5件)： アポトーシス ,  結腸直腸癌 ,  metastasis ,  ソラソジン ,  β-カテニン

分類 (1件)： 腫ようの実験的治療  (GE02040Y)

物質索引 (1件)： ソラソジン

引用文献 (45件)：

• Ferlay J, Ervik M, Dikshit R et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015; 136: E359-86.
• Ece E, Suayib Y. Maintenance strategy in metastatic colorectal cancer: a systematic review. Cancer Treat Rev 2016; 42: 82-90.
• Kim KY, Cha IH, Ahn JB et al. Estimating the adjuvant chemotherapy effect in elderly stage II and III colon cancer patients in an observational study. J Surg Oncol 2013; 107: 613-8.
• Markowitz SD, Bertagnolli MM. Molecular origins of cancer: Molecular basis of colorectal cancer. N Engl J Med 2009; 361: 2449-60.
• Goss KH, Groden J. Biology of the adenomatous polyposis coli tumor suppressor. J Clin Oncol 2000; 18: 1967-79.

タイトルに関連する用語 (9件)： ソラソジン ,  Akt ,  グリコーゲンシンターゼキナーゼ-3β ,  β-カテニン ,  経路 ,  ヒト ,  結腸直腸 ,  癌細胞 ,  阻害