文献

J-GLOBAL ID：201702259638598971   整理番号：17A0519283

重度の未治療喘息小児におけるオマリズマブの長期安全性,有効性,薬物動態および薬力学

Long-term safety, efficacy, pharmacokinetics and pharmacodynamics of omalizumab in children with severe uncontrolled asthma

著者 (18件)： Odajima Hiroshi (Department of Pediatrics, Fukuoka National Hospital) ,  Ebisawa Motohiro (Department of Allergy, Clinical Research Center for Allergology and Rheumatology, Sagamihara National Hospital) ,  Nagakura Toshikazu (Yoga Allergy Clinic) ,  Fujisawa Takao (Institute for Clinical Research, Mie National Hospital) ,  Akasawa Akira (Division of Allergy, Tokyo Metropolitan Children’s Medical Center) ,  Ito Komei (Department of Allergy, Aichi Children’s Health and Medical Center) ,  Doi Satoru (Department of Pediatrics, Osaka Prefectural Medical Center for Respiratory and Allergic Diseases) ,  Yamaguchi Koichi (Department of Pediatrics, The Fraternity Memorial Hospital) ,  Katsunuma Toshio (Department of Pediatrics, Jikei Daisan Hospital) ,  Kurihara Kazuyuki (Department of Allergy, Kanagawa Children’s Medical Center) ,  Teramoto Takahide (Department of Pediatrics, Graduate School of Medicine, Gifu University) ,  Sugai Kazuko (Department of Pediatrics, Fukuyama Medical Center) ,  Nambu Mitsuhiko (Department of Pediatrics, Tenri Hospital) ,  Hoshioka Akira (Department of Allergy and Rheumatology, Chiba Children’s Hospital) ,  Yoshihara Shigemi (Department of Pediatrics, Dokkyo Medical University) ,  Sato Norio (Clinical Development, Novartis Pharma K.K.) ,  Seko Noriko (Clinical Development, Novartis Pharma K.K.) ,  Nishima Sankei (Department of Pediatrics, Fukuoka National Hospital)
資料名： Allergology International  (Allergology International)
巻： 66  号： 1  ページ： 106-115(J-STAGE)  発行年： 2017年 
JST資料番号： L6446A  ISSN： 1323-8930  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 背景:オマリズマブは中度から重度のアレルギー性喘息小児におい...

シソーラス用語： 長期投与 ,...
準シソーラス用語： 薬物有害事象 ,...

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著者キーワード (10件)： Childhood asthma ,  Efficacy ,  Omalizumab ,  Safety evaluation ,  Total IgE ,  Childhood asthma ,  Efficacy ,  Omalizumab ,  Safety evaluation ,  Total IgE

分類 (2件)： 免疫療法薬・血液製剤の臨床への応用  (GW22020O) ,  呼吸器疾患の薬物療法  (GI05020J)

引用文献 (44件)：

• 1. Rabe KF, Adachi M, Lai CK, Soriano JB, Vermeire PA, Weiss KB, et al. Worldwide severity and control of asthma in children and adults: the global asthma in-sights and reality surveys. J Allergy Clin Immunol 2004;114:40-7.
• 2. Chipps BE, Szefler SJ, Simons FE, Haselkorn T, Mink DR, Deniz Y, et al. De-mographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma. J Allergy Clin Immunol 2007;119:1156-63.
• 3. Haselkorn T, Fish JE, Zeiger RS, Szefler SJ, Miller DP, Chipps BE, et al. Consis-tently very poorly controlled asthma, as defined by the impairment domain of the expert panel report 3 guidelines, increases risk for future severe asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) study. J Allergy Clin Immunol 2009;124: 895-902.e1-4.
• 4. Chipps BE, Zeiger RS, Dorenbaum A, Borish L, Wenzel SE, Miller DP, et al. Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort. Curr Respir Care Rep 2012;1:259-69.
• 5. Diette GB, Markson L, Skinner EA, Nguyen TT, Algatt-Bergstrom P, Wu AW. Nocturnal asthma in children affects school attendance, school performance, and parents' work attendance. Arch Pediatr Adolesc Med 2000;154:923-8.

タイトルに関連する用語 (9件)： 治療 ,  喘息 ,  小児 ,  オマリズマブ ,  長期 ,  安全性 ,  有効性 ,  薬物動態 ,  薬力学