文献

J-GLOBAL ID：201702260762787832   整理番号：17A0615255

runt関連転写因子2の発現の原因となる差次的DNAメチル化領域

The differentially DNA-methylated region responsible for expression of runt-related transcription factor 2

著者 (5件)： WAKITANI Shoichi (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  WAKITANI Shoichi (Laboratory of Veterinary Anatomy, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  YOKOI Daigo (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  HIDAKA Yuichi (Laboratory of Veterinary Surgery, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan) ,  NISHINO Koichiro (Laboratory of Veterinary Biochemistry and Molecular Biology, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki 889-2192, Japan)
資料名： Journal of Veterinary Medical Science (Web)  (Journal of Veterinary Medical Science (Web))
巻： 79  号： 2  ページ： 230-237(J-STAGE)  発行年： 2017年 
JST資料番号： U1094A  ISSN： 1347-7439  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： Runt関連転写因子2(Runx2)は骨形成に必須である。本...

シソーラス用語： *転写因子 ,...

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著者キーワード (5件)： correlation analysis ,  DNA methylation ,  osteogenesis ,  promoter ,  Runx2

分類 (2件)： 骨格系  (EJ10030R) ,  遺伝子発現  (EC02040Q)

引用文献 (27件)：

• 1. Banerjee, C., Javed, A., Choi, J. Y., Green, J., Rosen, V., van Wijnen, A. J., Stein, J. L., Lian, J. B. and Stein, G. S. 2001. Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype. Endocrinology 142: 4026-4039.
• 2. Byon, C. H., Javed, A., Dai, Q., Kappes, J. C., Clemens, T. L., Darley-Usmar, V. M., McDonald, J. M. and Chen, Y. 2008. Oxidative stress induces vascular calcification through modulation of the osteogenic transcription factor Runx2 by AKT signaling. J. Biol. Chem. 283: 15319-15327.
• 3. Cho, Y. D., Yoon, W. J., Kim, W. J., Woo, K. M., Baek, J. H., Lee, G., Ku, Y., van Wijnen, A. J. and Ryoo, H. M. 2014. Epigenetic modifications and canonical wingless/int-1 class (WNT) signaling enable trans-differentiation of nonosteogenic cells into osteoblasts. J. Biol. Chem. 289: 20120-20128.
• 4. Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L. and Karsenty, G. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89: 747-754.
• 5. Engelse, M. A., Neele, J. M., Bronckers, A. L., Pannekoek, H. and de Vries, C. J. 2001. Vascular calcification: expression patterns of the osteoblast-specific gene core binding factor alpha-1 and the protective factor matrix gla protein in human atherogenesis. Cardiovasc. Res. 52: 281-289.

タイトルに関連する用語 (4件)： 転写因子 ,  発現 ,  原因 ,  DNAメチル化