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J-GLOBAL ID：201702268664589350   整理番号：17A1483855

2015の幼児における呼吸器合胞体ウイルスによる急性下気道感染症の世界的,地域的および国疾患負担の推定:系統的レビューとモデリング研究【Powered by NICT】

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

著者 (120件)： Shi Ting (Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK) ,  McAllister David A (Institute of Health and Wellbeing, University of Glasgow, Scotland, UK) ,  O’Brien Katherine L (Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MS, USA) ,  Simoes Eric A F (University of Colorado, Aurora, CO, USA) ,  Madhi Shabir A (Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa) ,  Madhi Shabir A (Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa) ,  Gessner Bradford D (Agence de Medecine Preventive, Paris, France) ,  Polack Fernando P (Fundacion INFANT, Buenos Aires, Argentina) ,  Balsells Evelyn (Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK) ,  Acacio Sozinho (Centro de Investigacao em Saude de Manhica (CISM), Maputo, Mozambique) ,  Aguayo Claudia (Epidemiology Department, Ministry of Health, Chile) ,  Alassani Issifou (Ministry of Health, Togo) ,  Ali Asad (Department of Pediatrics and Child Health, Aga Khan University, Pakistan) ,  Antonio Martin (Medical Research Council Unit The Gambia, Basse, The Gambia) ,  Awasthi Shally (Department of Pediatrics, King George’s Medical University, Lucknow (UP), India) ,  Awori Juliet O (Kenya Medical Research Institute-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya) ,  Azziz-Baumgartner Eduardo (International Centre for Diarrhoeal Disease Research, Bangladesh) ,  Azziz-Baumgartner Eduardo (Centers for Disease Control and Prevention, Atlanta, GA, USA) ,  Baggett Henry C (Global Disease Detection Center, Thailand Ministry of Public Health-US Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand) ,  Baggett Henry C (Division of Global Health Protection, Centers for Disease Control and Prevention, Atlanta, GA, USA) ,  Baillie Vicky L (Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa) ,  Balmaseda Angel (Ministry of Health, Nicaragua) ,  Barahona Alfredo (Hospital Materno Infantil Jose Domingo de Obaldia, Ciudad De David, Chiriqui, Panama) ,  Basnet Sudha (Center for International Health, University of Bergen, Norway) ,  Basnet Sudha (Department of Child Health, Tribhuvan University Institute of Medicine, Nepal) ,  Bassat Quique (Centro de Investigacao em Saude de Manhica (CISM), Maputo, Mozambique) ,  Bassat Quique (ISGlobal, Barcelona Ctr Int Health Res (CRESIB), Hospital Clinic - Universitat de Barcelona, Barcelona, Spain) ,  Bassat Quique (ICREA, Pg Lluis Companys 23, 08010 Barcelona, Spain) ,  Basualdo Wilma (Hospital General Pediatrico Ninos de Acosta Nu, Ministerio de Salud Publica y Bienestar Social, San Lorenzo, Paraguay) ,  Bigogo Godfrey (Kenya Medical Research Institute, Centre for Global Health Research, Kisumu, Kenya) ,  Bont Louis (Wilhelmina Children’s Hospital, University Medical Center Utrecht, The Netherlands) ,  Breiman Robert F (Emory Global Health Institute, Emory University, AT, USA) ,  Brooks W Abdullah (Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MS, USA) ,  Brooks W Abdullah (International Centre for Diarrhoeal Disease Research, Bangladesh) ,  Broor Shobha (All India Institute of Medical Sciences, New Delhi, India) ,  Bruce Nigel (Department of Public Health and Policy, University of Liverpool, Liverpool, UK) ,  Bruden Dana (Arctic Investigations Program, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Centres for Disease Control and Prevention, Anchorage, AK, USA) ,  Buchy Philippe (Institute Pasteur Cambodia, Children’s Hospital Colorado, Aurora, CO, USA) ,  Buchy Philippe (GSK Vaccines Singapore, Children’s Hospital Colorado, Aurora, CO, USA) ,  Campbell Stuart (Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, Scotland, UK) ,  Carosone-Link Phyllis (Department of Pediatric Infectious Diseases, Children’s Hospital Colorado, Aurora, CO, USA) ,  Chadha Mandeep (National Institute of Virology, Pune, India) ,  Chipeta James (University Teaching Hospital, Lusaka, Zambia) ,  Chou Monidarin (Rodolphe Merieux Laboratory, Faculty of Pharmacy, University of Health Sciences, Phnom Penh, Cambodia) ,  Clara Wilfrido (Centers for Disease Control and Prevention, Central American Region, Guatemala City, Guatemala) ,  Cohen Cheryl (Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa) ,  Cohen Cheryl (School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa) ,  de Cuellar Elizabeth (Hospital San Juan de Dios, Santa Ana, Ministry of Health, El Salvador) ,  Dang Duc-Anh (National Institute of Hygiene and Epidemiology, Hanoi, Vietnam) ,  Dash-yandag Budragchaagiin (Bayanzurkh District General Hospital, Ulaanbaatar, Mongolia) ,  Deloria-Knoll Maria (Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MS, USA) ,  Dherani Mukesh (Department of Public Health and Policy, University of Liverpool, Liverpool, UK) ,  Eap Tekchheng (Department of Pneumology, National Pediatric Hospital, Phnom Penh, Cambodia) ,  Ebruke Bernard E (Medical Research Council Unit The Gambia, Basse, The Gambia) ,  Echavarria Marcela (Centro de Educacion Medica envestigaciones Clinicas “CEMIC”, Argentina) ,  de Freitas Lazaro Emediato Carla Cecilia (Health Secretariat of the City of Belo Horizonte, Brazil) ,  Fasce Rodrigo A (Public Health Institute, Chile) ,  Feikin Daniel R (Centers for Disease Control and Prevention, Atlanta, GA, USA) ,  Feng Luzhao (Division of Infectious Disease, Key Laboratory of Surveillance and Early-warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing, China) ,  Gentile Angela (Epidemiology Department, Austral University and Ricardo Gutierrez Children Hospital, Argentina) ,  Gordon Aubree (Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA) ,  Goswami Doli (Department of International Health, International Vaccine Access Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, MS, USA) ,  Goswami Doli (International Centre for Diarrhoeal Disease Research, Bangladesh) ,  Goyet Sophie (Institute Pasteur Cambodia, Children’s Hospital Colorado, Aurora, CO, USA) ,  Groome Michelle (Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa) ,  Groome Michelle (Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa) ,  Halasa Natasha (Vanderbilt University, Nashville, TN, USA) ,  Hirve Siddhivinayak (KEM Hospital Research Center, Pune, India) ,  Homaira Nusrat (International Centre for Diarrhoeal Disease Research, Bangladesh) ,  Homaira Nusrat (School of Women’s and Children’s Health, Faculty of Medicine, University of New South Wales, NSW, Australia) ,  Howie Stephen R C (Medical Research Council Unit The Gambia, Basse, The Gambia) ,  Howie Stephen R C (Department of Paediatrics, University of Auckland, Auckland, New Zealand) ,  Howie Stephen R C (Centre for International Health, University of Otago, Dunedin, New Zealand) ,  Jara Jorge (Center for Health Studies, Universidad del Valle de Guatemala, Guatemala) ,  Jroundi Imane (ISGlobal, Barcelona Ctr Int Health Res (CRESIB), Hospital Clinic - Universitat de Barcelona, Barcelona, Spain) ,  Jroundi Imane (Unit of Training and Research in Public Health, School of Medicine and Pharmacy of Rabat, University Mohamed V, Rabat, Morocco) ,  Kartasasmita Cissy B (University of Padjdjaran, Bandung, Indonesia) ,  Khuri-Bulos Najwa (University of Jordan, Amman, Jordan) ,  Kotloff Karen L ,  Krishnan Anand (All India Institute of Medical Sciences, New Delhi, India) ,  Libster Romina (Fundacion INFANT, Buenos Aires, Argentina) ,  Libster Romina (Vanderbilt University, Nashville, TN, USA) ,  Libster Romina ,  Lopez Olga ,  Lucero Marilla G ,  Lucion Florencia (Epidemiology Department, Austral University and Ricardo Gutierrez Children Hospital, Argentina) ,  Lupisan Socorro P ,  Marcone Debora N (Centro de Educacion Medica envestigaciones Clinicas “CEMIC”, Argentina) ,  McCracken John P (Center for Health Studies, Universidad del Valle de Guatemala, Guatemala) ,  Mejia Mario ,  Moisi Jennifer C (Agence de Medecine Preventive, Paris, France) ,  Montgomery Joel M ,  Moore David P (Medical Research Council: Respiratory and Meningeal Pathogens Research Unit, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa) ,  Moore David P (Department of Science and Technology/National Research Foundation: Vaccine Preventable Diseases, University of the Witwatersrand, Johannesburg, South Africa) ,  Moraleda Cinta (ISGlobal, Barcelona Ctr Int Health Res (CRESIB), Hospital Clinic - Universitat de Barcelona, Barcelona, Spain) ,  Moyes Jocelyn (Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, Johannesburg, South Africa) ,  Moyes Jocelyn (School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa) ,  Munywoki Patrick (Kenya Medical Research Institute-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya) ,  Munywoki Patrick ,  Mutyara Kuswandewi (University of Padjdjaran, Bandung, Indonesia) ,  Nicol Mark P ,  Nokes D James (Kenya Medical Research Institute-Wellcome Trust Research Programme, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya) ,  Nokes D James ,  Nymadawa Pagbajabyn ,  da Costa Oliveira Maria Tereza (Health Secretariat of the City of Belo Horizonte, Brazil) ,  Oshitani Histoshi ,  Pandey Nitin (Department of Pediatrics, King George’s Medical University, Lucknow (UP), India) ,  Paranhos-Baccala Glaucia ,  Phillips Lia N ,  Picot Valentina Sanchez ,  Rahman Mustafizur (International Centre for Diarrhoeal Disease Research, Bangladesh) ,  Rakoto-Andrianarivelo Mala ,  Rasmussen Zeba A ,  Rath Barbara A ,  Robinson Annick ,  Romero Candice ,  Russomando Graciela ,  Salimi Vahid ,  Sawatwong Pongpun (Global Disease Detection Center, Thailand Ministry of Public Health-US Centers for Disease Control and Prevention Collaboration, Nonthaburi, Thailand) ,  Scheltema Nienke (Wilhelmina Children’s Hospital, University Medical Center Utrecht, The Netherlands)
資料名： Lancet  (Lancet)
巻： 390  号： 10098  ページ： 946-958  発行年： 2017年 
JST資料番号： B0673A  ISSN： 0140-6736  CODEN： LANCA  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 著者らは以前,呼吸器合胞体ウイルス(RSV)は,2005年に5歳未満の小児における死亡55000~199000をもたらす急性下気道感染(ALRI)(重症)の全エピソードの22%と関連していることを推定した。過去5年間では,RSVに関する主要な研究活性は発展途上国からの実質的な新しいデータを得た。大国際協力からかなり拡張データセットを用いて,著者らは2015の幼児におけるRSV ALRIエピソードからの地球規模発生率,入院率,死亡率を推定することを目的とした。1995年1月1日,2016年12月31日の間に公表された研究の系統的レビューおよび76種の高品質の地域住民ベース研究由来の未発表データから年齢と世界銀行の所得領域により層別化した5歳未満の小児におけるRSV関連ALRI(RSV ALRI)の発生率と入院率を推定した。リスク因子ベースモデルと2015個体群推定量を用いた132発展途上国のためのRSV ALRI発生率を推定した。病院(発表された,および未発表の)研究から入院推定値と入院症例死亡比率を結合することによる院内RSV ALRI死亡率を推定した。も群集とRSV活性におけるALRI死亡率の月別データを報告した研究を同定することにより,全体的RSV ALRI死亡率を推定した。RSV ALRIの三億三千百万(不確実性範囲[UR]216 503),2015年にグローバルには約三千二百万(27 38)入院,および5歳未満の小児における59600(48000 74500)院内死亡をもたらすことを推定した。6か月未満の小児では,一千四百万(UR 12 17)入院,および27300(UR 20700 36200)院内死亡したRSV ALRIに起因した。全体RSV ALRI死亡率は118200(UR 94600 149400)高くなる可能性があると推定した。発生率と死亡率は,与えられた母集団では年毎に実質的に変化した。全体的に,RSVは小児ALRIの一般的な原因と幼児における入院の主要な原因であり,ヘルスケアサービスに大きな負荷をもたらした。RSV ALRIによる入院および院内死亡の約45%は6か月未満の小児に発生する。有効母体RSVワクチンやモノクローナル抗体はこの年齢群における疾病負担に実質的な影響を持つ可能性がある。Bill&Melindaゲート基礎。Copyright 2017 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： モノクローナル抗体 ,  病院 ,  危険因子 ,  *システマティックレビュー ,  入院 ,  *幼児 ,  個体群 ,  *モデリング ,  不確実性 ,  発展途上国 ,  *RSウイルス ,  死亡率 ,  子供
準シソーラス用語： 入院率 ,  発生率 , 【Automatic Indexing@JST】

分類 (1件)： 感染症・寄生虫症一般  (GD01010H)

タイトルに関連する用語 (11件)： 幼児 ,  呼吸器合胞体ウイルス ,  下気道感染症 ,  世界 ,  地域 ,  疾患 ,  負担 ,  推定 ,  系統的レビュー ,  モデリング ,  研究