文献

J-GLOBAL ID：201702270355926183   整理番号：17A0633293

表面バイオマーカーに対するナノボディはブドウ膜メラノーマ患者由来異種移植片における腫瘍の遺伝的異種性分析を可能にする

Nanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts

著者 (29件)： Crepin Ronan (Tumor Target and Therapeutic Antibody - Identification Platform (TAb-IP), Paris Cedex 05, France) ,  Gentien David (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Duche Angeline (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Rapinat Audrey (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Reyes Cecile (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Nemati Fariba (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Massonnet Gerald (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Decaudin Didier (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Decaudin Didier (Medical Oncology Department, Institut Curie, Paris Cedex 05, France) ,  Djender Selma (Tumor Target and Therapeutic Antibody - Identification Platform (TAb-IP), Paris Cedex 05, France) ,  Djender Selma (Institut Curie, PSL Research University, Paris Cedex 05, France) ,  Moutel Sandrine (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  Moutel Sandrine (Institut Curie, PSL Research University, Paris Cedex 05, France) ,  Moutel Sandrine (UMR144, Institut Curie, Paris, France) ,  Desrumeaux Klervi (Tumor Target and Therapeutic Antibody - Identification Platform (TAb-IP), Paris Cedex 05, France) ,  Cassoux Nathalie (Department of Surgical Oncology, Institut Curie, Paris, France) ,  Piperno-Neumann Sophie (Department of Medical Oncology, Institut Curie, Paris, France) ,  Amigorena Sebastian (Institut Curie, PSL Research University, Paris Cedex 05, France) ,  Amigorena Sebastian (INSERM Unit 932, Paris cedex 05, France) ,  Amigorena Sebastian (SIRIC INCa-DGOS-4654, Paris, France) ,  Amigorena Sebastian (CIC IGR Curie 1428, Paris, France) ,  Perez Franck (Tumor Target and Therapeutic Antibody - Identification Platform (TAb-IP), Paris Cedex 05, France) ,  Perez Franck (Institut Curie, PSL Research University, Paris Cedex 05, France) ,  Perez Franck (UMR144, Institut Curie, Paris, France) ,  Roman-Roman Sergio (Translational Research Department, Institut Curie, PSL Research University, Paris, France) ,  de Marco Ario (Tumor Target and Therapeutic Antibody - Identification Platform (TAb-IP), Paris Cedex 05, France) ,  de Marco Ario (SIRIC INCa-DGOS-4654, Paris, France) ,  de Marco Ario (CIC IGR Curie 1428, Paris, France) ,  de Marco Ario (Department of Biomedical Sciences and Engineering, University of Nova Gorica (UNG), Vipava, Slovenia)
資料名： Pigment Cell & Melanoma Research  (Pigment Cell & Melanoma Research)
巻： 30  号： 3  ページ： 317-327  発行年： 2017年05月 
JST資料番号： T0984A  ISSN： 1755-1471  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： イギリス (GBR)  言語： 英語 (EN)

抄録/ポイント： ブドウ膜メラノーマ(UM)細胞の表面上に発現するバイオマーカ...

シソーラス用語： *ぶどう膜疾患 ,...
準シソーラス用語： *ブドウ膜メラノーマ ,...

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著者キーワード (7件)： nanobodies ,  uveal melanoma ,  patient-derived xenografts ,  MUC18 ,  membrane surface biomarkers ,  panning ,  tumor polyclonality

分類 (1件)： 基礎腫よう学一般  (GE02010R)

引用文献 (53件)：

• Aliprandi, M., Sparacio, E., Pivetta, F. et al. (2010). The availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins. J. Biomed. Biotechnol. ID 658954.
• Amirouchene-Angelozzi, N., Nemati, F., Gentien, D. et al. (2014). Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target. Mol. Oncol. 8, 1508-1520.
• Angi, M., Kalirai, H., Prendergast, S. et al. (2016). In-depth proteomic profiling of the uveal melanoma secretome. Oncotarget 7, 49623- 49635.
• Bande, M.F., Santiago, M., Muinelo-Romay, L. et al. (2015). Detection of circulating melanoma cells in choroidal melanocytic lesions. BMC Res. Notes 8, 452.
• Beutel, J., Wegner, J., Wegner, R. et al. (2009). Possible implications of MCAM expression in metastasis and non-metastatic of primary uveal melanoma patients. Curr. Eye Res. 34, 1004-1009.

タイトルに関連する用語 (8件)： バイオマーカー ,  ナノボディ ,  ブドウ膜メラノーマ ,  患者 ,  異種移植片 ,  腫瘍 ,  異種性 ,  分析