文献

J-GLOBAL ID：201702271525553762   整理番号：17A0504320

強力なワクチン抗原特異的全身性,粘膜体液性免疫応答を誘発する新規抗原放出リング装置を用いた膣内免疫

Intravaginal immunisation using a novel antigen-releasing ring device elicits robust vaccine antigen-specific systemic and mucosal humoral immune responses

著者 (8件)： McKay Paul F. (Imperial College London, Department of Medicine, Division of Infectious Diseases, Section of Virology, Norfolk Place, London W2 1PG, UK) ,  Mann Jamie F.S. (Imperial College London, Department of Medicine, Division of Infectious Diseases, Section of Virology, Norfolk Place, London W2 1PG, UK) ,  Pattani Aditya (School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK) ,  Kett Vicky (School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK) ,  Aldon Yoann (Imperial College London, Department of Medicine, Division of Infectious Diseases, Section of Virology, Norfolk Place, London W2 1PG, UK) ,  King Deborah (Imperial College London, Department of Medicine, Division of Infectious Diseases, Section of Virology, Norfolk Place, London W2 1PG, UK) ,  Malcolm R. Karl (School of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK) ,  Shattock Robin J. (Imperial College London, Department of Medicine, Division of Infectious Diseases, Section of Virology, Norfolk Place, London W2 1PG, UK)
資料名： Journal of Controlled Release  (Journal of Controlled Release)
巻： 249  ページ： 74-83  発行年： 2017年03月10日 
JST資料番号： C0308D  ISSN： 0168-3659  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： ワクチン学者にとって病原体侵入の粘膜部位における抗原特異的免...

シソーラス用語： *ワクチン ,...
準シソーラス用語： *免疫応答 ,...

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分類 (3件)： 婦人科・産科の基礎医学  (GS01020L) ,  免疫療法薬・血液製剤の基礎研究  (GW22010D) ,  生物薬剤学(基礎)  (GY01021U)

引用文献 (33件)：

• P.F. McKay, A.V. Cope, J.F. Mann, S. Joseph, M. Esteban, R. Tatoud, et al., Glucopyranosyl lipid A adjuvant significantly enhances HIV specific T and B cell responses elicited by a DNA-MVA-protein vaccine regimen, PLoS One 9 (1) (2014), e84707. http://dx.doi.org/10.1371/journal.pone.0084707 (PubMed PMID: 24465426; PubMed Central PMCID: PMC3900398).
• P.F. McKay, D.F. King, J.F. Mann, G. Barinaga, D. Carter, RJ. Shattock, TLR4 and TLR7/8 adjuvant combinations generate different vaccine antigen-specific immune outcomes in Minipigs when administered via the ID or IN routes, PLoS One 11 (2) (2016), e0148984. http://dx.doi.org/10.1371/journal.pone.0148984 (PubMed PMID: 26862758; PubMed Central PMCID: PMC4749393).
• M. Habibi, M.R. Asadi Karam, M.A. Shokrgozar, M. Oloomi, A. Jafari, S. Bouzari, Intranasal immunization with fusion protein MrpH・FimH and MPL adjuvant confers protection against urinary tract infections caused by uropathogenic Escherichia coli and Proteus mirabilis, Mol. Immunol. 64 (2) (2015) 285-294, http://dx.doi.org/10.1016/j.molimm.2014.12.008 (PubMed PMID: 25562574).
• H.Y. Wu, S. Abdu, D. Stinson, M.W. Russell, Generation of female genital tract anti-body responses by local or central (common) mucosal immunization, Infect. Immun. 68 (10) (2000) 5539-5545 (PubMed PMID: 10992451; PubMed Central PMCID: PMC101503).
• J. Mestecky, M.W. Russell, Induction of mucosal immune responses in the human genital tract, FEMS Immunol. Med. Microbiol. 27 (4) (2000) 351-355 (PubMed PMID: 10727891).

タイトルに関連する用語 (10件)： ワクチン抗原 ,  全身 ,  粘膜 ,  体液性免疫 ,  応答 ,  誘発 ,  抗原 ,  放出 ,  膣 ,  免疫