文献

J-GLOBAL ID：201702280142892549   整理番号：17A0087882

アナグレリドによるヒト一次巨核球の分化の阻害:遺伝子発現プロファイリング分析

Inhibition of human primary megakaryocyte differentiation by anagrelide: a gene expression profiling analysis

著者 (12件)： Sakurai Kazuki (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Fujiwara Tohru (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Fujiwara Tohru (Molecular Hematology/Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Hasegawa Shin (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Okitsu Yoko (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Fukuhara Noriko (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Onishi Yasushi (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Yamada-Fujiwara Minami (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Yamada-Fujiwara Minami (Division of Blood Transfusion and Cell Therapy, Tohoku University Hospital, Sendai, Japan) ,  Ichinohasama Ryo (Department of Hematopathology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Harigae Hideo (Department of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan) ,  Harigae Hideo (Molecular Hematology/Oncology, Tohoku University Graduate School of Medicine, Sendai, Japan)
資料名： International Journal of Hematology  (International Journal of Hematology)
巻： 104  号： 2  ページ： 190-199  発行年： 2016年08月 
JST資料番号： F0888A  ISSN： 0925-5710  CODEN： IJHEEY  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： ドイツ (DEU)  言語： 英語 (EN)

抄録/ポイント： アナグレリドは,本態性血小板減少症患者に対する治療選択肢であ...

シソーラス用語： 巨核球 ,...
準シソーラス用語： 本態性血小板減少症 ,...

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著者キーワード (5件)： Anagrelide ,  Essential thrombocythemia ,  FLI1 ,  TAL1 ,  Megakaryocytic differentiation

分類 (2件)： 血液の基礎医学  (GK01020N) ,  血液・体液作用薬の基礎研究  (GW14010M)

物質索引 (1件)： アナグレリド

引用文献 (34件)：

• Passamonti F, Rumi E, Arcaini L, Boveri E, Elena C, Pietra D, et al. Prognostic factors for thrombosis, myelofibrosis, and leukemia in essential thrombocythemia: a study of 605 patients. Haematologica. 2008;93:1645-51.
• Palandri F, Catani L, Testoni N, Ottaviani E, Polverelli N, Fiacchini M, et al. Long-term follow-up of 386 consecutive patients with essential thrombocythemia: safety of cytoreductive therapy. Am J Hematol. 2009;84:215-20.
• Harrison CN, Campbell PJ, Buck G, Wheatley K, East CL, Bareford D, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med. 2005;353:33-45.
• Gisslinger H, Gotic M, Holowiecki J, Penka M, Thiele J, Kvasnicka HM, et al. Anagrelide compared with hydroxyurea in WHO-classified essential thrombocythemia: the ANAHYDRET Study, a randomized controlled trial. Blood. 2013;121:1720-8.
• Fleming JS, Buyniski JP. A potent new inhibitor of platelet aggregation and experimental thrombosis, anagrelide (BL-4162A). Thromb Res. 1979;15:373-88.

タイトルに関連する用語 (7件)： アナグレリド ,  ヒト ,  巨核球 ,  分化 ,  阻害 ,  遺伝子発現プロファイリング ,  分析