文献

J-GLOBAL ID：201702286558579864   整理番号：17A0040946

ブスルファンにより生じる出血時間延長を伴う急性血小板減少症のブタモデル

A swine model of acute thrombocytopenia with prolonged bleeding time produced by busulfan

著者 (9件)： Abe Tomoyuki (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan) ,  Abe Tomoyuki (Division of Stem Cell Research and Drug Development, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan) ,  Kono Shota (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan) ,  Kono Shota (Division of Stem Cell Research and Drug Development, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan) ,  Ohnuki Takahiro (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan) ,  Hishikawa Shuji (Division for Medical Skill Training, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan) ,  Kunita Satoshi (Division of Development of Animal Resource, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan) ,  Hanazono Yutaka (Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi 329-0498, Japan) ,  Hanazono Yutaka (Division of Stem Cell Research and Drug Development, Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan)
資料名： Experimental Animals  (Experimental Animals)
巻： 65  号： 4  ページ： 345-351(J-STAGE)  発行年： 2016年 
JST資料番号： Z0755A  ISSN： 1341-1357  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 血小板減少症の動物モデルは,止血剤,凍結血小板,人工血小板の...

シソーラス用語： ブタ ,...
準シソーラス用語： 骨髄抑制

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著者キーワード (5件)： large animal model ,  busulfan ,  pig ,  prolonged bleeding time ,  thrombocytopenia

分類 (1件)： 血液の基礎医学  (GK01020N)

物質索引 (1件)： ブスルファン

引用文献 (26件)：

• 1. Abe T., Masuda S., Tanaka Y., Nitta S., Kitano Y., Hayashi S., Hanazono Y., and Nagao Y. 2012. Maternal administration of busulfan before in utero transplantation of human hematopoietic stem cells enhances engraftments in sheep. Exp. Hematol. 40: 436-444.
• 2. Aiuti A., Cattaneo F., Galimberti S., Benninghoff U., Cassani B., Callegaro L., Scaramuzza S., Andolfi G., Mirolo M., Brigida I., Tabucchi A., Carlucci F., Eibl M., Aker M., Slavin S., Al-Mousa H., Al Ghonaium A., Ferster A., Duppenthaler A., Notarangelo L., Wintergerst U., Buckley R.H., Bregni M., Marktel S., Valsecchi M.G., Rossi P., Ciceri F., Miniero R., Bordignon C., and Roncarolo M.G. 2009. Gene therapy for immunodeficiency due to adenosine deaminase deficiency. N. Engl. J. Med. 360: 447-458.
• 3. Bassols A., Costa C., Eckersall P.D., Osada J., Sabrià J., and Tibau J. 2014. The pig as an animal model for human pathologies: A proteomics perspective. Proteomics Clin. Appl. 8: 715-731.
• 4. Blajchman M.A. 1999. Substitutes for success. Nat. Med. 5: 17-18.
• 5. Blajchman M.A. and Lee D.H. 1997. The thrombocytopenic rabbit bleeding time model to evaluate the in vivo hemostatic efficacy of platelets and platelet substitutes. Transfus. Med. Rev. 11: 95-105.

タイトルに関連する用語 (5件)： ブスルファン ,  出血 ,  血小板減少症 ,  ブタ ,  モデル