文献

J-GLOBAL ID：201702287159301103   整理番号：17A1688912

術後再発時にアレクチニブにより治療に成功したEGFR変異とALK転座を有する二重原発性肺腺癌の症例

The case of double primary lung adenocarcinomas with an EGFR mutation and ALK translocation successfully treated with alectinib at the post-surgical recurrence

著者 (12件)： Tsunezuka Yoshio (Department of General Thoracic Surgery, Ishikawa Prefectural Central Hospital) ,  Tanaka Nobuyoshi (Department of General Thoracic Surgery, Ishikawa Prefectural Central Hospital) ,  Fujimori Hideki (Department of General Thoracic Surgery, Ishikawa Prefectural Central Hospital) ,  Togashi Yuki (Pathology Project for Molecular Targets, The Cancer Institute, Japanese Foundation for Cancer Research) ,  Baba Satoko (Pathology Project for Molecular Targets, The Cancer Institute, Japanese Foundation for Cancer Research) ,  Takeuchi Kengo (Pathology Project for Molecular Targets, The Cancer Institute, Japanese Foundation for Cancer Research) ,  Katayanagi Kazuyoshi (Department of Pathology, Ishikawa Prefectural Central Hospital) ,  Kurumaya Hiroshi (Department of Pathology, Ishikawa Prefectural Central Hospital) ,  Kitade Hironori (Chemotherapy Center, Houju Memorial Hospital) ,  Atagi Shinji (Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center) ,  Yano Seiji (Chemotherapy Center, Houju Memorial Hospital) ,  Yano Seiji (Department of Medical Oncology, Kanazawa University Cancer Research Institute, Kanazawa University)
資料名： Journal of Medical Investigation (Web)  (Journal of Medical Investigation (Web))
巻： 64  号： 3.4  ページ： 305-307(J-STAGE)  発行年： 2017年 
JST資料番号： U0711A  ISSN： 1349-6867  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： 日本 (JPN)  言語： 英語 (EN)

抄録/ポイント： 36歳の男性の肺の右下部葉に2個の結節を見出した。手術切除後...

シソーラス用語： *腺癌 ,...
準シソーラス用語： *原発性肺腺癌 ,...

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著者キーワード (4件)： EGFR mutation ,  EML4-ALK ,  double cancers ,  alectinib

分類 (4件)： 腫ようの薬物療法  (GE03032C) ,  血液の腫よう  (GK04000M) ,  術後処置・予後  (GC07050M) ,  呼吸器の腫よう  (GI04000G)

引用文献 (6件)：

• 1. Inamura K, Takeuchi K, Togashi Y, Hatano S, Ninomiya H, Motoi N, Mun MY, Sakao Y, Okumura S, Nakagawa K, Soda M, Choi YL, Mano H, Ishikawa Y: EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol 22: 508-515, 2009
• 2. Togashi Y, Soda M, Sakata S, Sugawara E, Hatano S, Asaka R, Nakajima T, Mano H, Takeuchi K: KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only. PLoS One 7: e31323, 2012
• 3. Seto T, Kiura K, Nishio M, Nakagawa K, Maemondo M, Inoue A, Hida T, Yamamoto N, Yoshioka H, Harada M, Ohe Y, Nogami N, Takeuchi K, Shimada T, Tanaka T, Tamura T: CH5424802 (RO5424802) for patients with ALK-rearranged advanced non-small-cell lung cancer (AF-001JP study): a single-arm, open-label, phase 1-2 study. Lancet Oncol 14: 590-598, 2013
• 4. Toyokawa G, Taguchi K, Ohba T, Morodomi Y, Takenaka T, Hirai F, Yamaguchi M, Seto T, Takenoyama M, Sugio K, Ichinose Y: First case of combined small-cell lung cancer with adenocarcinoma harboring EML4-ALK fusion and an exon 19 EGFR mutation in each histological component. J Thorac Oncol 7: e39-41, 2012
• 5. Miyanaga A, Shimizu K, Noro R, Seike M, Kitamura K, Kosaihira S, Minegishi Y, Shukuya T, Yoshimura A, Kawamoto M, Tsuchiya S, Hagiwara K, Soda M, Takeuchi K, Yamamoto N, Mano H, Ishikawa Y, Gemma A: Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4-ALK-rearranged non-small-cell lung cancer harbored coexisting EGFR mutation. BMC Cancer 13: 262, 2013

タイトルに関連する用語 (10件)： 術後再発 ,  アレクチニブ ,  治療 ,  成功 ,  EGFR ,  変異 ,  ALK ,  転座 ,  原発性肺腺癌 ,  症例