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J-GLOBAL ID：201702291019190395   整理番号：17A2005231

膨大細胞腫の発症機構の解析【Powered by NICT】

Etiopathogenesis of oncocytomas

著者 (20件)： Correia Marcelo (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Correia Marcelo (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Pinheiro Pedro (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Pinheiro Pedro (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Batista Rui (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Batista Rui (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Batista Rui (Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Soares Paula (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Soares Paula (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Soares Paula (Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Soares Paula (Department of Pathology, Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Sobrinho-Simoees Manuel (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Sobrinho-Simoees Manuel (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Sobrinho-Simoees Manuel (Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Sobrinho-Simoees Manuel (Department of Pathology, Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Sobrinho-Simoees Manuel (Department of Pathology, Centro Hospitalar Sao Joao, Porto, Portugal) ,  Maximo Valdemar (Cancer Signalling and Metabolism Research Group, Instituto de Investigacao e Inovacao em Saude - i3S (Institute for Research and Innovation in Health), University of Porto, Porto, Portugal) ,  Maximo Valdemar (Cancer Signalling and Metabolism Research Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal) ,  Maximo Valdemar (Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal) ,  Maximo Valdemar (Department of Pathology, Faculdade de Medicina da Universidade do Porto - FMUP (Medical Faculty of University of Porto), Porto, Portugal)
資料名： Seminars in Cancer Biology  (Seminars in Cancer Biology)
巻： 47  ページ： 82-94  発行年： 2017年 
JST資料番号： W0473A  ISSN： 1044-579X  資料種別： 逐次刊行物 (A)
記事区分： 原著論文  発行国： オランダ (NLD)  言語： 英語 (EN)

抄録/ポイント： 膨大細胞腫は,欠陥の異常な蓄積によって特徴づけられる明確な腫瘍と腫瘍の細胞質における機能不全ミトコンドリア(おそらく)である。この特別な表現型は,過去数十年間研究されてきたと疾病原因原因の明確化がまだ必要とされている。膨大細胞腫の形成と維持に関与するいくつかの機構が合理的な原因として受け入れられているが,膨大細胞形質転換のためのそれぞれの関連性と寄与は,異なる癌疾病原因文脈に依存する可能性がある。本レビューでは,腫瘍細胞形質転換につながる可能性がある疾病原因事象の現在の知識を記述し,腫瘍進行とミトコンドリア蓄積に対するそれらの寄与を論じた。Copyright 2018 Elsevier B.V., Amsterdam. All rights reserved. Translated from English into Japanese by JST.【Powered by NICT】

シソーラス用語： オートファジー ,  *病因 ,  細胞質 ,  表現型 ,  腫瘍 ,  ミトコンドリア
準シソーラス用語： 腫瘍進行 ,  *発症機構 ,  *好酸性細胞腺腫 , 【Automatic Indexing@JST】

著者キーワード (5件)： 膨大細胞腫 ,  ミトコンドリアリッチ腫瘍 ,  mtDNA ,  オートファジー ,  マイトファジー

分類 (1件)： 腫ようの化学・生化学・病理学  (GE02030N)

タイトルに関連する用語 (3件)： 膨大細胞腫 ,  発症 ,  解析