木原隆典

キハラタカノリ | Kihara Takanori

所属機関・部署：
職名：教授
ホームページURL (1件)： https://takanori-kihara.jimdo.com/

研究分野 (3件)：細胞生物学 , 生体材料学 , 生体医工学

研究キーワード (10件)：コラーゲン , 細胞接着 , 間葉系幹細胞 , 細胞外マトリックス , ナノバイオテクノロジー , Deep Learning , 細胞工学 , 原子間力顕微鏡 , 平滑筋細胞 , 石灰化

競争的資金等の研究課題 (11件)：

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論文 (42件)：

Do, T.L, Tachibana, K, Yamamoto, N, Ando, K, Isoda, T, Kihara, T. Interaction of SARS-CoV-2 Spike protein with ACE2 induces cortical actin modulation, including dephosphorylation of ERM proteins and reduction of cortical stiffness. Human Cell. 2025. 38. 3
Tachibana, K, Nakamura, Y, Do, T.L, Kihara, T, Kawada, H, Yamamoto, N, Ando, K. Mutations in the SARS-CoV-2 Spike proteins affected the ACE2-binding affinity during the development of Omicron pandemic variants. Biochem Biophys Res Commun. 2024. 719. 150120
Phan, T.K.T, Do, T.L, Tachibana, K, Kihara, T. Alpha-mangostin dephosphorylates ERM to induce adhesion and decrease surface stiffness in KG-1 cells. Human Cell. 2022. 35. 1. 189-198
Kihara, T, Matsumoto, T, Nakahashi, Y, Tachibana, K. Mechanical stiffness softening and cell adhesion are coordinately regulated by ERM dephosphorylation in KG-1 cells. Human Cell. 2021. 34. 6. 1709-1716
Thi Kieu Trang Phan, Fahimeh Shahbazzadeh, Takanori Kihara. Alpha-mangostin reduces mechanical stiffness of various cells. Human Cell. 2020. 33. 2. 347-355

MISC (16件)：

木原隆典, 立花宏一. 機械的物性から読み取る白血球接着. Medical Science Digest. 2022. 48. 11. 46-47
Takanori Kihara. Three-dimensional mineralized tissue formation of cultured bone marrow stromal cells. Hyper Bio Assembler for 3D Cellular Systems. 2015. 317-326
Shinohara, S, Shinohara, S, Kihara, T, Miyake, J. Regulation of differentiated phenotypes of vascular smooth muscle cells. Current Basic and Pathological Approaches to the Function of Muscle Cells and Tissues - From Molecules to Humans. 2012. 331-344
木原隆典, 中村史, 三宅淳. ナノニードルによる細胞内分子評価と生体適合性高分子の利用. ファインケミカル. 2011. 4. 10. 33-40
中村史, 雨宮陽介, 木原隆典, 三宅淳. FRET分子プローブ修飾ナノニードルを用いた細胞内解析技術の開発. 表面科学. 2010. 31. 9. 459-465

学歴 (3件)：

学位 (1件)：

経歴 (6件)：

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受賞 (5件)：

2017 - 2017 Kyushu-Seibu/Pusan-Gyeongnam Joint Symposium on High Polymer (18th) and Fibers (16th) Poster Presentation Award Alpha-mangostin inhibits migration and invasion of cancer cells
2016 - Interdisciplinary Medial, Dental and Soft-material Researches on the move -Showcase Review in Kitakyushu- Award for Best Poster Presentation How do osteogenic cells form calcified matrix?
2015 - リバネス第26回リバネス研究費富士フイルム賞石灰化に対する各種細胞外基質分子の効果
2012 - 22nd Anniversary World Congress on Biosensors Best Paper Award 2012 Winner Evaluation of the actin cytoskeleton state using an antibody-functionalized nanoneedle and AFM
2008 - NanoBio Seoul 2008 Best Poster Award of NanoBio-Seoul 2008 Development of in situ molecular sensor by using nanoneedle technology

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木原 隆典