松浦徹

マツウラトオル | MATSUURA TORU

所属機関・部署：
職名：講師

研究分野 (3件)：発生生物学 , 分子生物学 , 細胞生物学

研究キーワード (5件)：オルガノイド , フィードバック制御 , 合成生物学 , 幹細胞 , 時間生物学

競争的資金等の研究課題 (9件)：

2022 - 2025 副腎皮質オルガノイドを用いた自家移植法の開発
2022 - 2025 哺乳類胚の着床を可能とする細胞間相互作用の解明
2019 - 2022 大腸がん組織内での概日周期多様性とその治療への応用
2016 - 2017 Amplified productions of biomaterials using synthetic biology
2016 - 2017 Second-generation biofuel production with genetically engineered Neurospora crassa

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論文 (39件)：

Andrew E Rosselot, Miri Park, Mari Kim, Toru Matsu-Ura, Gang Wu, Danilo E Flores, Krithika R Subramanian, Suengwon Lee, Nambirajan Sundaram, Taylor R Broda, et al. Ontogeny and function of the circadian clock in intestinal organoids. The EMBO Journal. 2022. 41. 2. e106973
Kang Kug (Paul) Lee, 松浦徹, Andrew E. Rosselot, Taylor R. Broda, James M. Wells, Christian I. Hong. 3次元小腸マイクロチップを長期間培養するための泡除去装置付きのマイクロ流路デバイスの開発. 2021. 15. 1. 014110
Chan C, Ooashi N, Akiyama H, Fukuda T, Inoue M, Matsu-Ura T, Shimogori T, Mikoshiba K, Kamiguchi H. Inositol 1,4,5-Trisphosphate Receptor Type 3 Regulates Neuronal Growth Cone Sensitivity to Guidance Signals. iScience. 2020. 23. 3. 100963
Toru Matsu-ura, Hideki Shirakawa, Kenichi G. N. Suzuki, Akitoshi Miyamoto, Kotomi Sugiura, Takayuki Michikawa, Akihiro Kusumi, Katsuhiko Mikoshiba. Dual-FRET imaging of IP3 and Ca2+ revealed Ca2+-induced IP3 production maintains long lasting Ca2+ oscillations in fertilized mouse eggs. Scientific Reports. 2019. 9. 1. 4829-11
Toru Matsu-Ura, Andrey A. Dovzhenok, Samuel T. Coradetti, Krithika R. Subramanian, Daniel R. Meyer, Jaesang J. Kwon, Caleb Kim, Nathan Salomonis, N. Louise Glass, Sookkyung Lim, et al. Synthetic Gene Network with Positive Feedback Loop Amplifies Cellulase Gene Expression in Neurospora crassa. ACS Synthetic Biology. 2018. 7. 5. 1395-1405

MISC (6件)：

Toru Matsu-ura, Andrey Dovzhenok, Sookyung Lim, Christian I. Hong. Development of Synthetic Gene Circuits to Amplify the Production of Biomaterials, Cellulases, and Lentivirus. BIOPHYSICAL JOURNAL. 2016. 110. 3. 317A-317A
Toru Matsu-Ura, Jill Pruszka, Eitaro Aihara, Andrey A. Dovzhenok, Marshall H. Montrose, Sookkyung Lim, Sean R. Moore, Christian Hong. Robust Coupling of Cell Cycle and Circadian Rhythms in Mouse Enteroids. GASTROENTEROLOGY. 2015. 148. 4. S157-S157
M. Arizono, H. Bannai, K. Nakamura, F. Niwa, M. Enomoto, T. Matsu-ura, A. Miyamoto, M. W. Sherwood, T. Nakamura, K. Mikoshiba. Receptor-selective diffusion barrier enhances sensitivity of astrocytic processes to metabotropic glutamate receptor stimulation. JOURNAL OF NEUROCHEMISTRY. 2012. 123. 116-116
Toru Matsu-ura, Sachiko Ishida, Takayiki Michikawa, Katsuhiko Mikoshiba. The Relationship Between Ip(3) Level and the Frequency of Ca2+ Oscillations. BIOPHYSICAL JOURNAL. 2011. 100. 3. 83-83
Takayuki Michikawa, Tadashi Shinohara, Masahiro Enomoto, Jun-Ichi Goto, Miwako Iwai, Toru Matsu-ura, Haruka Yamazaki, Akitoshi Miyamoto, Akio Suzuki, Katsuhiko Mikoshiba. Mechanistic basis of the bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium. NEUROSCIENCE RESEARCH. 2011. 71. E84-E84

特許 (6件)：

AMPLIFIED PRODUCTION OF MONOCLONAL ANTIBODIES
Lentivirus Packaging System Comprising a Synthetic Positive Feedback Loop
NEUROSPORA CRASSA STRAINS WITH AMPLIFIED EXPRESSION OF CELLULASES AND PRODUCTION OF BIOFUEL THEREFROM
Endoplasmic reticulum cal-cium ATPase kinetics in-dicator and use thereof
A new IP3R binding protein and its application for IP3 indicator

書籍 (3件)：

講演・口頭発表等 (18件)：

胚の着床率向上に寄与する薬剤の選別
(第13回スクリーニング学研究会 2022)
関西医科大学(KMU)オルガノイドバンクの取り組み
(第13回スクリーニング学研究会 2022)
Single cell RNA sequencing revealed circadian heterogeneity and circadian dependent cell population changes in mouse epithelial tissues
(日本時間生物学会学術大会 2021)
ホスホイノシチド代謝の新しい経路
(第43回日本分子生物学会 2020)
多色細胞系譜追跡法を用いた歯肉接合上皮細胞のクローナリティ解析
(第63回秋季日本歯周病学会学術大会 2020)

学歴 (3件)：

学位 (1件)：

経歴 (5件)：

受賞 (8件)：

2021 - 加多乃会和田喜代子賞ミニ子宮を用いた哺乳類初期胚の着床及び発生の研究
2020 - 公益財団法人武田科学振興財団医学系研究助成子宮オルガノイドを用いたマウス胚の着床及び発生の試験管内再現
2016 - University of Cincinnati UC technology commercialization accelerator funding Phase II Amplified productions of biomaterials using synthetic biology.
2016 - Ohio Department of Higher Education Innovation Corps Ohio (I-CORPS@Ohio) Second-generation biofuel production with genetically engineered Neurospora crassa.
2015/05 - American Gastroenterological Association (AGA)/AGA-Gastroenterology Research Group (GRG) AGA/AGA-GRG Fellow Abstract Prize Robust Coupling of Cell Cycle and Circadian Rhythms in Mouse Enteroids

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所属学会 (3件)：

Biophysical Society , 日本分子生物学会 , 日本時間生物学会

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松浦 徹