研究者
J-GLOBAL ID:201801005462238525   更新日: 2021年04月11日

田口 歩

Taguchi Ayumu
所属機関・部署:
職名: 分野長
研究分野 (3件): 分子生物学 ,  消化器内科学 ,  腫瘍診断、治療学
研究キーワード (7件): ノンコーディングRNA ,  がん ,  肺がん ,  消化器がん ,  マイクロRNA ,  バイオマーカー ,  プロテオミクス
競争的資金等の研究課題 (15件):
  • 2017 - 2022 Development of Risk and Early Detection Biomarker for Small Cell Lung Cancer
  • 2018 - 2022 Circulating Exosomes as Biomarkers for Lung Cancer Early Detection
  • 2016 - 2021 Pathogenesis and Early Progression of Lung Cancer
  • 2018 - 2021 Circulating Exosomes as Biomarkers for Lung Cancer Early Detection
  • 2015 - 2020 Integrative molecular profiling for discovery of biomarkers and therapeutic targets in epithelial cancer
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論文 (30件):
  • Martin Pichler, Cristian Rodriguez-Aguayo, Su Youn Nam, Mihnea Paul Dragomir, Recep Bayraktar, Simone Anfossi, Erik Knutsen, Cristina Ivan, Enrique Fuentes-Mattei, Sang Kil Lee, et al. Therapeutic potential of FLANC, a novel primate-specific long non-coding RNA in colorectal cancer. Gut. 2020
  • Shiels M, Kirk G, M. Drummond B, Dhillon D, Hanash S, Taguchi A, Engels E. HIV infection and Circulating Levels of Pro-Surfactant Protein B and Surfactant Protein D. J Infect Dis. 2018. 7. 413-417
  • Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, et al. A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2018. djy126
  • Integrative Analysis of Lung, Cancer Etiology, Risk, INTEGRAL) Consortium for Early Detection of Lung Cancer, Guida F, Sun N, Bantis LE, Muller DC, Li P, Taguchi A, Dhillon D, et al. Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins. JAMA Oncol. 2018. e182078
  • Jody Vykoukal, Nan Sun, Clemente Aguilar-Bonavides, Hiroyuki Katayama, Ichidai Tanaka, Johannes F. Fahrmann, Michela Capello, Junya Fujimoto, Mitzi Aguilar, Ignacio I. Wistuba, et al. Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma. ONCOTARGET. 2017. 8. 56. 95466-95480
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MISC (50件):
  • Robert S. Bresalier, James C. Byrd, Dean E. Brenner, Hans J. Nielsen, Ziding Feng, Suyu Liu, Samir Hanash, Ayumu Taguchi, John A. Baron, Sapna Syngal, et al. A BLOOD-BASED MARKER PANEL FOR DETECTION OF COLORECTAL NEOPLASIA. GASTROENTEROLOGY. 2017. 152. 5. S1316-S1316
  • Mattias A. Johansson, Ayumu Taguchi, David Muller, Samir Hanash, Paul Brennan. Comprehensive evaluation of promising biomarkers for lung cancer risk prediction. CANCER RESEARCH. 2016. 76
  • Michela Capello, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Dilsher S. Dhillon, Hong Wang, James L. Abbruzzese, Anirban Maitra, Margaret A. Tempera, Randall Brand, et al. Sequential validation of blood-based protein biomarker candidates for early-stage pancreatic cancer. CANCER RESEARCH. 2016. 76
  • Johannes F. Fahrmann, Jennifer Dennison, Eunice Murage, Hong Wang, Edwin J. Ostrin, Ayumu Taguchi, Samir Hanash. Elevated kynureninase protein expression is associated with KEAP1 mutant non-small cell lung cancer and is predictive of poor overall survival. CANCER RESEARCH. 2016. 76
  • Roxana S. Redis, Luz E. Vela, Weiqin Lu, Juliana Ferreira de Oliveira, Cristina Ivan, Cristian Rodriguez-Aguayo, Douglas Adamoski, Barbara Pasculli, Ayumu Taguchi, Yunyun Chen, et al. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 (vol 61, pg 520, 2016). MOLECULAR CELL. 2016. 61. 4. 640-640
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特許 (2件):
  • Methods for the Detection and Treatment of Pancreatic Cancer
  • Methods for the Detection and Treatment of Lung Cancer.
書籍 (1件):
  • Molecular Oncology: Causes of Cancer and Targets for Treatment.
    Cambridge University Press. 2013
講演・口頭発表等 (14件):
  • 基礎と臨床の融合が拓く癌バイオマーカー研究の新展開
    (名古屋大学大学院医学系研究科 2018)
  • Molecular Diagnostics: Back-and-forth Crosstalk between Basic and Clinical Research to Fight Cancer
    (愛知県がんセンター 2018)
  • 基礎と臨床をつなぐバイオマーカー研究の展開
    (愛知県がんセンター 2017)
  • Blood-based biomarkers for early detection of cancer.
    (MD Anderson Cancer Center 2016)
  • Molecular cancer biomarkers in the era of precision medicine.
    (Nagoya University Graduate School of Medicine 2016)
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学歴 (3件):
  • 2001 - 2005 名古屋大学大学院医学系研究科
  • 1991 - 1997 名古屋大学医学部
  • 1988 - 1991 東海高校
経歴 (11件):
  • 2018/11 - 現在 名古屋大学大学院医学系研究科 がん先端診断・治療開発学講座 先端がん診断学分野 連携教授
  • 2018/09 - 現在 愛知県がんセンター 分子診断トランスレーショナルリサーチ分野 分野長
  • 2018/04 - 2018/08 テキサス大学大学院 Graduate School of Biomedical Sciences Assistant Professor
  • 2015/09 - 2018/08 MDアンダーソンがんセンター Cancer Protein Biomarker Facility Leader
  • 2013/11 - 2018/08 MDアンダーソンがんセンター Department of Translational Molecular Pathology Assistant Professor (tenure track)
全件表示
委員歴 (5件):
  • 2018 - MD Anderson Cancer Centner 審査委員、Institutional Research Grant
  • 2017 - MD Anderson Cancer Center 審査委員、The Internal Review Study Section (INTEREST)
  • 2017 - MD Anderson Cancer Center 審査委員、Sister Institution Network Funding (SINF) Program
  • 2015 - The National Science Centre 審査委員、OPUS 8
  • 2014 - Connecticut Bioscience Innovation Fund (CBIF) 審査委員、AAAS Scientific and Technical Merit Review
受賞 (3件):
  • 2018 - American Cancer Society Research Scholar Award
  • 2015 - U.S. Department of Defence Lung Cancer Research Program Career Development Award
  • 2008 - 米国がん学会 Scholar-in-Training Award
所属学会 (7件):
日本消化器がん検診学会 ,  日本消化器内視鏡学会 ,  米国臨床腫瘍学会 ,  米国癌学会 ,  日本消化器病学会 ,  日本内科学会 ,  日本癌学会
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