深見達基

フカミタツキ | Fukami Tatsuki

所属機関・部署：
職名：准教授

研究分野 (2件)：医療薬学 , 薬系衛生、生物化学

研究キーワード (4件)：薬物代謝 , 医薬品毒性 , non-P450酵素 , 遺伝子多型

競争的資金等の研究課題 (11件)：

全件表示

論文 (169件)：

Soshi Shinohara, Seijo Uchijima, Keiya Hirosawa, Mai Nagaoka, Masataka Nakano, Miki Nakajima, Tatsuki Fukami. Arylacetamide deacetylase regulates hepatic iron homeostasis to protect against carbon tetrachloride-induced ferroptosis. Archives of toxicology. 2024. 98. 12. 4059-4075
Rei Sato, Tatsuki Fukami, Kazuya Shimomura, Yongjie Zhang, Masataka Nakano, Miki Nakajima. Characterization of human alcohol dehydrogenase 4 and aldehyde dehydrogenase 2 as enzymes involved in the formation of 5-carboxylpirfenidone, a major metabolite of pirfenidone. Drug metabolism and disposition: the biological fate of chemicals. 2024
Shiori Hashiba, Masataka Nakano, Itsuki Yokoseki, Etsushi Takahashi, Masayuki Kondo, Yoichi Jimbo, Naoki Ishiguro, Hiroshi Arakawa, Tatsuki Fukami, Miki Nakajima. Cytochrome P450 and UDP-glucuronosyltransferase expressions, activities, and induction abilities in 3D-cultured human renal proximal tubule epithelial cells. Drug metabolism and disposition: the biological fate of chemicals. 2024
Shimon Nakashima, Tatsuki Fukami, Takashi Kudo, Masataka Nakano, Akiko Matsui, Naoki Ishiguro, Miki Nakajima. Iminium ion metabolites are formed from nintedanib by human CYP3A4. Drug metabolism and pharmacokinetics. 2024. 57. 101025-101025
Mai Nagaoka, Yoshiyuki Sakai, Miki Nakajima, Tatsuki Fukami. Role of carboxylesterase and arylacetamide deacetylase in drug metabolism, physiology, and pathology. Biochemical pharmacology. 2024. 223. 116128-116128

MISC (16件)：

講演・口頭発表等 (24件)：

Effects of miR-222-3p-mediated downregulation of arylacetamide deacetylase on drug hydrolysis and lipid accumulation
(The 26th North American ISSX Meeting and 39th JSSX Meeting 2024)
Novel mechanism of drug-metabolizing hydrolases regulating the toxicity caused by reactive metabolites
(The 26th North American ISSX Meeting and 39th JSSX Meeting 2024)
Novel characteristics of non-P450 oxidases unraveled from functional analyses
(The 25th International Symposium on Microsomes and Drug Oxidations 2024)
機能解析から紐解かれたnon-P450酸化・還元酵素の新たな特徴
(第30回HAB研究機構学術年会 2023)
アシルグルクロニドおよびアシルCoA抱合体の生成を制御する反応 / 酵素の特徴づけ
(日本薬物動態学会第37回年会 2022)

学歴 (3件)：

学位 (1件)：

経歴 (4件)：

2015/02 - 現在金沢大学医薬保健研究域薬学系准教授
2016/03 - 2016/12 National Institute of Health National Cancer Institute Special Volunteer
2008/10 - 2015/01 金沢大学医薬保健研究域薬学系助教
2006/04 - 2008/09 日本学術振興会特別研究員(DC1)

委員歴 (7件)：

全件表示

受賞 (2件)：

所属学会 (4件)：

International Society for the Study of Xenobiotics , 日本毒性学会 , 日本薬物動態学会 , 日本薬学会

※　J-GLOBALの研究者情報は、researchmapの登録情報に基づき表示しています。登録・更新については、こちらをご覧ください。

深見 達基