研究者
J-GLOBAL ID:201801007103478360
更新日: 2024年09月20日
戸田 侑紀
Yuki Toda
研究分野 (2件):
血液、腫瘍内科学
, 薬系衛生、生物化学
研究キーワード (3件):
がん転移
, がん微小環境
, 低酸素
競争的資金等の研究課題 (4件):
- 2023 - 2027 肺前転移ニッチにおける乳酸アシドーシス発症因子の同定
- 2020 - 2023 骨髄腫幹細胞のexosome分泌型miRNAを介した低酸素生存適応
- 2019 - 2022 細胞指向性送達理論に基づくエクソソーム捕捉型核酸医薬による多発性骨髄腫治療の開発
- 2014 - 2016 エクソソームのがん細胞指向性解析に基づく高選択的薬物送達法の開発
論文 (22件):
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Daiki Shimizu, Miku Ishibashi, Tadaaki Yamada, Yuki Toda, Shigekuni Hosogi, Eishi Ashihara. POLD1 Is Required for Cell Cycle Progression by Overcoming DNA Damage in Malignant Pleural Mesothelioma. Cancer genomics & proteomics. 2024. 21. 2. 158-165
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Yusuke Sano, Naoko Kuwabara, Saori Nakagawa, Yuki Toda, Shigekuni Hosogi, Shinji Sato, Eishi Ashihara. Hypoxia-adapted Multiple Myeloma Stem Cells Resist γδ-T-Cell-mediated Killing by Modulating the Mevalonate Pathway. Anticancer research. 2023. 43. 2. 547-555
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Toma Matsui, Yuki Toda, Haruka Sato, Rina Itagaki, Kazuya Konishi, Anna Moshnikova, Oleg A Andreev, Shigekuni Hosogi, Yana K Reshetnyak, Eishi Ashihara. Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy. Frontiers in oncology. 2023. 13. 1258442-1258442
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Yuki Sugiyama, Seikou Nakamura, Yuichi Tokuda, Masakazu Nakano, Yasunao Hattori, Hiroki Nishiguchi, Yuki Toda, Shigekuni Hosogi, Masayuki Yamashita, Kei Tashiro, et al. 7,8-Dihydroxy-3-(4′-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells. Biochemical and Biophysical Research Communications. 2023. 638. 200-209
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Emi Soma, Asako Yamayoshi, Yuki Toda, Yuji Mishima, Shigekuni Hosogi, Eishi Ashihara. Successful Incorporation of Exosome-Capturing Antibody-siRNA Complexes into Multiple Myeloma Cells and Suppression of Targeted mRNA Transcripts. Cancers. 2022. 14. 3. 566-566
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MISC (2件):
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芦原 英司, 今吉 菜月, Yoshioka Makoto, 中田 晋, Chauhan Jay, 戸田 侑紀, Fletcher Steven, Strovel Jeffrey, 高田 和幸. 新規治療薬 基礎 新規ブロモドメイン阻害剤CG13250の多発性骨髄腫に対する抗腫瘍効果. International Journal of Myeloma. 2017. 7. 1. 41-41
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Natsuki Imayoshi, Makoto Yoshioka, Susumu Nakata, Jay Chauhan, Yoko Kado, Yuki Toda, Steven Fletcher, Jeffrey Strovel, Kazuyuki Takata, Eishi Ashihara. A Novel BRD4 Inhibitor CA2 Suppresses MM Cell Proliferation in an Orthotopic Myeloma Mouse Model. BLOOD. 2016. 128. 22
受賞 (2件):
- 2024/08 - Frankfurt Cancer Conference 2024 Selected speaker
- 2019/05 - 第44回日本骨髄腫学会学術集会優秀ポスター賞
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